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A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.

An elderly man with dementia suffered limb damage from rubber bands around his leg, highlighting the need for careful monitoring to prevent such injuries.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Educating healthcare workers and parents about hair toe tourniquets can help prevent serious complications.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

A young man with high-grade prostate cancer had successful surgery and good recovery, highlighting the need for awareness in younger men.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The patient has a rare skin condition that shows features of two known disorders.

Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.

The document is a detailed medical reference on skin and genetic disorders.

Early detection and skin biopsies are crucial for treating skin cancer and diagnosing various skin conditions.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.