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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.

Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

Certain medications, especially 5-α reductase inhibitors and neuropsychiatric drugs, are often linked to erectile dysfunction.

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Scrotal rejuvenation treats aging-related changes in men's scrotum using methods like medication, hair transplantation, and surgery.

Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.

Cord blood platelets may have promising future medical uses but need more research.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Stem cell treatment improved life quality and sexual function in women with hair loss.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

Scientists created a 3D skin model to study a chronic skin disease and test treatments.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Some cancer treatments can cause permanent hair loss.

Androgens can cause hair growth in some areas but hair loss on the scalp.

Androgens can both increase body hair and cause scalp hair loss.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.

A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.