2 citations
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March 2024 in “Supportive Care in Cancer” In this study, manual cold capping was found to be effective in minimizing chemotherapy-induced alopecia, with 92.1% of patients retaining 50% or more of their hair, although effectiveness varied with different chemotherapy regimens.
22 citations
,
May 2016 in “Breast cancer research and treatment” This study reported cold thermal injuries on the scalp in four patients using cold caps to prevent chemotherapy-induced alopecia, suggesting improper application can lead to adverse events.
3 citations
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November 2018 in “Oncology issues” This article discusses the emerging field of supportive oncodermatology, which collaborates between oncology and dermatology to address skin-related side effects of cancer treatments, and reports no new clinical results.
53 citations
,
April 2018 in “Journal of The American Academy of Dermatology” This article reviews therapy-related hair disorders in oncology patients, detailing underlying mechanisms and potential management strategies, but reports no new clinical findings.
10 citations
,
May 2018 in “Nutrition and Cancer” This article reviews current research on spice-derived nutraceuticals for treating melanoma and skin cancer, noting emerging evidence that these natural substances may offer preventative and protective benefits against cancer, amidst increased global interest.
37 citations
,
October 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This literature review reported that scalp hypothermia significantly decreases the occurrence of chemotherapy-induced alopecia, increasing effectiveness by 2.7-fold in controlled clinical trials and 3.9-fold in randomized trials, and highlighted a need for standard guidelines for its use.
6 citations
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June 2023 in “American Society of Clinical Oncology Educational Book” This review highlights emerging strategies to manage chemotherapy side effects like nausea, neuropathy, and alopecia, noting that scalp cooling has been effective for reducing hair loss, while cryotherapy and cannabis show promise but need further study for side effect management.
17 citations
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June 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This paper provides an overview of scalp cooling as an effective and safe intervention for preventing chemotherapy-induced alopecia, addressing its impact on cancer patients and survivors.
103 citations
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December 2011 in “Journal of the American Academy of Dermatology” This review discusses current knowledge and management strategies for chemotherapy-induced alopecia, highlighting the need for better research prioritization and providing patient support materials, but reports no new clinical results.
62 citations
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February 2011 in “Expert review of dermatology” This review discusses the incidence, reversibility, and impact of chemotherapy-induced alopecia and concludes that scalp cooling is the most effective prevention method in most cases, though some questions remain.
38 citations
,
September 2017 in “Oncologist” This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.
1 citations
,
January 2018 in “Springer eBooks” The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
64 citations
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July 2011 in “Dermatologic Therapy” This review discusses treatments for chemotherapy-induced alopecia, highlighting scalp cooling for hair loss prevention and 2% topical minoxidil for regrowth acceleration as effective options, but reports a need for more rigorous trials to validate promising new therapies.
11 citations
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January 2022 in “Journal of Cancer” This article reviews the potential for low intensity ultrasound as an antidote for the peripheral cytotoxic side effects of taxane drugs in chemotherapy, presenting no new clinical results.
May 2026 in “Research Square” In this study, researchers found that chemotherapy-induced alopecia counseling and resource access are insufficient and influenced by socioeconomic factors such as employment, income, and education, underscoring the need for standardized education and improved resource availability to address disparities.
5 citations
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September 2024 in “Journal of Clinical Medicine” This article reviews the pathophysiology of chemotherapy-induced alopecia and reports that scalp cooling can reduce hair loss by 50% in patients with early breast cancer receiving chemotherapy, without compromising survival or increasing scalp metastasis risk.
September 2024 in “Current Oncology” This review discusses the common occurrence of docetaxel-induced hair loss in cancer patients, including permanent cases, and highlights current and experimental strategies like scalp cooling, minoxidil, and new clinical trials for managing and preventing this side effect.
5 citations
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July 2024 in “Journal of Market Access & Health Policy” This paper discusses the introduction and advantages of an Insurance-Based Billing Model for scalp cooling devices in the USA, which can enhance access to this treatment for reducing chemotherapy-induced alopecia, particularly benefiting underserved and disadvantaged populations.
6 citations
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April 2022 in “The Breast” This study found that scalp cooling significantly reduced chemotherapy-induced hair loss in breast cancer patients, especially those receiving taxane monotherapy, but did not significantly affect hair regrowth after chemotherapy.
3 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.
1 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study investigated pangolin skin genetics, finding that while sweat gland-related genes are not inactivated, several genes related to sebaceous gland function are, which highlights complex evolutionary adaptations in mammalian skin.
20 citations
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September 2013 in “Anti-Cancer Drugs” In this study, PTH-CBD effectively prevented and partially reversed chemotherapy-induced alopecia in mice, with pretreatment offering a better cosmetic outcome compared to therapeutic administration after hair loss onset.
March 2024 in “Research Square (Research Square)” In this study, scalp cooling therapy was found to be well tolerated and effective at improving hair preservation for Asian women with breast or gynecological cancers undergoing certain chemotherapy regimens, particularly weekly paclitaxel, compared to historical controls.
58 citations
,
March 2013 in “Human Reproduction Update” This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.
24 citations
,
November 2013 in “British Journal of Dermatology” This study found that chemotherapy in female breast cancer patients caused significant early hair loss, which began to recover three months after completion, whereas tamoxifen did not affect hair growth.
16 citations
,
September 2015 in “Journal of Ethnopharmacology” This review examines the long-standing use of "Dictamnus" in traditional medicine, highlighting the promising potential of D. albus and D. hispanicus as herbal drug candidates, but presents no new experimental findings.
14 citations
,
February 2000 in “Feminism & Psychology” This article discusses PCOS's limited public and feminist awareness and highlights the stress experienced by women with hirsutism, but presents no new research findings.
13 citations
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December 2018 in “Development, Growth & Differentiation” This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.
6 citations
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May 2020 in “Molecules/Molecules online/Molecules annual” This study found that while yak belly hair is chemically similar to human hair, its higher porosity and lower mechanical strength limit its usefulness as a substitute in hair dye development.
5 citations
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June 2012 in “QJM: An International Journal of Medicine” This article reviews the historical development of pharmacology up to the mid-20th century and outlines its transition from a support role in therapeutics to a distinct scientific discipline, but reports no new findings.