January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
2 citations
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December 2023 in “International journal of molecular sciences” This study reviews the complex keratinization process in the epidermis, detailing how various factors regulate keratinocyte differentiation and emphasizing the importance of understanding this process for the pathogenesis of skin disorders like ichthyoses and psoriasis.
1 citations
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April 2022 in “JAAD case reports” This case report describes a unique instance of IgG/IgA pemphigus in a Chinese woman, highlighting its distinct clinical and immunopathologic characteristics, including successful management with dapsone and prednisolone.
2 citations
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September 2004 in “Experimental Dermatology” This review discusses how dysfunction in keratinocyte adhesion affects skin integrity and conditions like alopecia and keratoderma, highlighting the roles of intercellular junctions, and reports no new clinical results.
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.
68 citations
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January 2008 in “Clinics in dermatology” This article reviews the principles and practices of Siddha medicine, discussing its traditional treatments for various skin and systemic diseases, but reports no new clinical results.
May 2025 in “Journal of the European Academy of Dermatology and Venereology” This study observed that early treatment with ritlecitinib in patients with alopecia areata, especially when severity is low, led to more favorable responses, and continued improvement was seen up to 24 months, offering guidance on treatment timing and duration.
This study reports that COVID-19 can trigger various dermatological autoimmune and autoinflammatory diseases, highlighting the need for clinicians to consider these potential connections during the pandemic.
February 2024 in “Curēus” This review highlights the critical importance of a balanced diet, with adequate proteins, vitamins, and minerals, to support skin health and potentially treat inflammatory skin conditions like psoriasis and atopic dermatitis, emphasizing the need for evidence-based dietary guidance.
March 2024 in “International journal of molecular sciences” This study suggests that abnormal levels of zinc, copper, and iron in serum or hair may serve as auxiliary and prognostic tests for various skin diseases, though further research is necessary due to conflicting data.
August 2023 in “Dermatology and Therapy” This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.
May 2022 in “Journal of Education, Health and Sport” This review discusses the associations between dermatological disorders and increased cardiovascular risk, emphasizing that skin conditions with chronic inflammation may elevate the likelihood of cardiovascular diseases.
February 2025 in “Animals” In this review, researchers examined the molecular diversity and expression patterns of major skin appendage proteins, like keratins and EDC proteins, in tetrapods, highlighting recent findings in reptiles and birds and identifying knowledge gaps for future research.
79 citations
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March 2017 in “Dermatologic clinics” This review discusses the complex systemic nature of vitiligo and its associations with autoimmune conditions, emphasizing the need for increased understanding and awareness of related comorbidities and psychological effects.
59 citations
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June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
49 citations
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December 2009 in “Journal of Investigative Dermatology” This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
2 citations
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May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study identified different skin disease profiles in primary versus secondary care in Florianopolis from 2016 to 2017, highlighting the primary care role in managing less complex conditions and referring complex cases for specialized dermatology care.
February 2021 in “Journal of Investigative Dermatology” This study found that specific junctional proteins are significantly downregulated in balding regions of the scalp in men with androgenetic alopecia, suggesting disrupted cell communication may play a role in hair loss.
1 citations
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January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
20 citations
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October 2003 in “The Journal of Dermatology” This study observed that while dexamethasone-cyclophosphamide pulse therapy is relatively free from hypertension and diabetes compared to conventional steroids in pemphigus patients, it frequently causes generalized weakness and flushing.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
24 citations
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October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
In this study, baricitinib treatment for severe alopecia areata was associated with complete hair regrowth after 12 months in two patients, suggesting it may be an effective alternative to traditional therapies, although safety and clinical implications need careful consideration.
May 2025 in “International Journal of Science and Research (IJSR)” In this case report, azathioprine induced sudden hair loss and pancytopenia in a 42-year-old female patient, but discontinuing the drug and providing supportive care resulted in complete recovery and hair regrowth within 2.5 months.
August 2025 in “Frontiers in Immunology” This case report is the first to document the coexistence of bullous pemphigoid, malignant tumors, and alopecia areata in a patient, highlighting the complete resolution of skin lesions with dupilumab and spontaneous hair regrowth without disease-specific treatment.
This case report details a 47-year-old female with atopic dermatitis who developed alopecia areata after six months on dupilumab therapy; treatment discontinuation and other interventions led to complete hair regrowth, suggesting dupilumab may trigger alopecia areata in patients with atopic or autoimmune predispositions.
December 2024 in “World s Veterinary Journal” This case study from Ukraine describes a 5-year-old Akita dog diagnosed with sebaceous adenitis, presenting with pruritus, alopecia, and inflammation; treatment over 30 days led to complete restoration of affected areas, implicating potential heritability in Akitas.
3 citations
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January 2017 in “International journal of research - granthaalayah” In this study, thirty participants applied a paste made from Elaeocarpus serratus and Psidium guajava leaves on their scalps, resulting in significant improvements in dandruff symptoms, with over 40% achieving complete remission and no adverse effects reported.
January 2025 in “International Journal of Molecular Sciences” This narrative review explored the complex interconnections between psoriasis and other dermatological conditions like vitiligo, alopecia areata, and atopic dermatitis, highlighting shared immune dysfunctions that complicate diagnosis and treatment, with implications for research and holistic patient care.
48 citations
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May 2008 in “Drug Discovery Today: Disease Mechanisms” This review discusses recent advancements in understanding hair follicles, their disorders, and potential therapeutic opportunities, but it reports no new clinical findings.