Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study confirmed that the novel solid lipid microparticle formulation of adapalene demonstrated follicular penetration potential and targeted particle erosion in sebum in in vitro tests.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

This study found that in mice lacking EGFR, elevated Wnt signaling disrupts hair follicle development by affecting cell proliferation and differentiation, revealing a critical role for EGFR in regulating these processes.

This review discusses recent advancements in cutaneous drug delivery technologies and the potential of transfollicular pathways for improved treatment of skin conditions, but reports no clinical results.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

This review discusses the aesthetic and dermatological uses of exogenous hyaluronic acid for skin rejuvenation and highlights the need for thorough investigation to confirm its claimed benefits, but it reports no new clinical findings.

In this study, researchers found that ligand homodimerization controls the receptor binding specificity of the FGF9 subfamily, preventing off-target activation of FGFR "b" isoforms.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This review examines the role of cyclodextrins in improving the solubility, stability, and bioavailability of steroid drugs but does not report new experimental findings.

This study demonstrated that a 3D air–liquid culture system using Wnt-CM-treated cells can induce hair regeneration in nude mice and may facilitate large-scale preparation for hair loss treatment.

This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.

This review describes the various cutaneous manifestations of essential thrombocythemia and how treatments like hydroxycarbamide, interferon-alfa, and anagrelide may lead to skin complications, but does not report new clinical findings.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.

This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.

The authors suggest that nanoparticles, synthesized from biological sources, may enable targeted cancer therapy with fewer side effects than traditional methods.

This review discusses zinc supplementation as a complementary therapy for chronic hepatitis C, noting its potential benefits in improving treatment outcomes and reducing side effects, but reports no new clinical results.

This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.

This review discusses age-related changes in scalp skin and their potential effects on hair follicle aging, but reports no new clinical results, calling for further investigation.

This study found a novel PAX9 gene mutation that may cause tooth agenesis and trichodysplasia in a studied family.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.

This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This review explores the skin regeneration process in spiny mice and highlights differences from laboratory mice, focusing on potential molecular and immune system roles without reporting new experimental results.

This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.