30 citations
,
July 2022 in “Scientific Reports” This study developed a model using cardiovascular radiomics to estimate biological heart age, finding obesity and other health factors strongly correlated with accelerated heart aging.
26 citations
,
August 2014 in “PubMed” This study found that testosterone treatment in older hypogonadal men caused minor improvements in depressive symptoms and visuospatial memory, but overall, major cognitive benefits were not observed.
26 citations
,
June 2000 in “Journal of The American Academy of Dermatology” This study found that older men with vertex balding had lower levels of IGFBP-3 and higher levels of IGF-1 in their plasma.
23 citations
,
August 2018 in “Anais Brasileiros De Dermatologia” This study found that patients with androgenetic alopecia reported more impact on their quality of life in terms of emotions, functioning, and symptoms than those with alopecia areata.
23 citations
,
January 2015 in “Journal of The American Academy of Dermatology” This study found that patients with myotonic dystrophy type 1 had higher numbers of nevi, dysplastic nevi, melanomas, and pilomatrixomas compared to age- and sex-matched controls.
23 citations
,
January 2010 in “Journal of Medical Primatology” This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
19 citations
,
September 2014 in “JAMA Dermatology” Eosinophilic infiltrate is not a reliable indicator for diagnosing chronic alopecia areata.
19 citations
,
June 2002 in “American Journal of Dermatopathology” This study found significant differences in bcl-2 expression between areas of the scalp affected and unaffected by androgenetic alopecia, suggesting a uniform follicle population or synchronized follicular cycling in affected areas.
17 citations
,
June 2020 in “Animals” This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.
16 citations
,
December 2018 in “Plant Science” This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.
15 citations
,
October 2018 in “Reproductive Biomedicine Online” This study suggests that the anogenital distance measure AGDAC may moderately discriminate the presence of polycystic ovarian syndrome and could be a useful clinical tool.
14 citations
,
April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
12 citations
,
September 2018 in “Naturwissenschaften” This study found that melatonin at 0.2 g/L for 72 hours most effectively enhances cashmere growth in Liaoning cashmere goats by upregulating the lncRNA MTC, which activates NF-kB signaling.
12 citations
,
January 2016 in “Journal of Clinical and Investigative Dermatology” This study examines how the Severity of Alopecia Tool score was used to assess Alopecia Areata in patients while excluding systemic conditions that might affect vitamin D levels, but reports no new clinical results.
11 citations
,
April 2020 in “Journal of Dermatological Treatment” This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
10 citations
,
September 2020 in “Biopolymers” This study found that bleached hair showed optimal protein structural integrity and tensile strength at pH 5, with significant changes in cross-linking, water content, and diameter at more alkaline or acidic levels.
9 citations
,
September 2015 in “Reproductive Biomedicine Online” This study suggests that longer GGN repeat polymorphisms in the androgen receptor gene are associated with polycystic ovary syndrome in women.
8 citations
,
November 2024 in “Scientific Reports” In this study, different drying methods for Hedychium spicatum rhizomes significantly affected the essential oil yield, antioxidant potential, and compound composition, with the HSOV30 method yielding the highest oil content, antioxidant activity, and specific compound levels such as 1,8-cineole and elemol.
7 citations
,
October 2020 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that stress plays a significant role in altering phenotypic features and body composition among PCOS patients, potentially worsening due to the COVID-19 pandemic.
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that the prevalence of androgenetic alopecia was significantly higher among smokers compared to nonsmokers, though the severity wasn't linked to smoking intensity.
6 citations
,
October 2022 in “Journal of cell science” This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.
5 citations
,
January 2010 in “The anatomical record” This study assessed hair whorl characteristics in domestic dogs and found that simple whorls predominate, with tufted whorls more common in specific regions like elbows and chests, influenced by factors such as coat traits and source.
4 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that ELL is crucial for maintaining the proliferative capacity of the basal layer in human epidermal keratinocytes by stabilizing RNA polymerase II at the transcription start site.
4 citations
,
January 2020 in “Cells” This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.
4 citations
,
December 2011 in “Journal of The American Academy of Dermatology” This study found that higher cumulative doses of topical minoxidil solution were strongly associated with improved hair density and thickness in male patients with androgenic alopecia over a 24-week period.
3 citations
,
November 2023 in “Journal of Computer Science and Engineering (JCSE)” This study observed that using the Fisher score feature selection approach with capsule network models led to a promising 94% accuracy in diabetes detection, indicating its potential as a diagnostic tool.
3 citations
,
May 2023 in “Precision clinical medicine” This study analyzed gene expression data to identify key genes involved in severe forms of alopecia areata, discovering four immune monitoring genes (LGR5, SHISA2, HOXC13, S100A3) with potential for early diagnosis and better understanding of the disease's biological mechanisms.
3 citations
,
September 2019 in “Clinical and experimental dermatology” This study found that basal cell carcinoma cells differentiate along hair follicle lineages and may be influenced by hair follicle cycle modulators for potential therapeutic targeting.
3 citations
,
June 2000 in “Journal of The American Academy of Dermatology” This study found that older men with vertex balding have lower circulating levels of the protein IGFBP-3 and higher levels of IGF-1.
2 citations
,
December 2024 In this study, the researchers observed that the evolution of Curtobacterium flaccumfaciens pv. flaccumfaciens, which causes tan spot in Australian mungbeans, is driven by clonal expansion from existing genetic variations, emphasizing the need for informed breeding strategies to manage resistance against this pathogen.