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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Testosterone's muscle-building effects do not require its conversion to DHT.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.