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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.

Finasteride effectively blocks enzyme causing male pattern baldness.

Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Testosterone's muscle-building effects do not require its conversion to DHT.