January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
300 citations,
October 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
57 citations,
October 2018 in “Journal of The American Academy of Dermatology” Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
25 citations,
November 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
18 citations,
July 2007 in “Hair transplant forum international” Platelet-rich plasma may improve healing and hair growth in hair transplant surgery.
12 citations,
October 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
10 citations,
August 2020 in “Journal of Bioscience and Bioengineering” Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
8 citations,
July 2019 in “Cell Proliferation” Researchers found a way to turn skin cells into cells that can grow new hair.
6 citations,
June 2020 in “Journal of Drugs in Dermatology” Platelet-rich plasma (PRP) showed promise for treating alopecia due to its regenerative, anti-inflammatory, and anti-bacterial properties. PRP contained growth factors like PDGF, TGF-β, VEGF, EGF, and IGF, which contributed to hair regrowth by binding to receptors on hair follicle stem cells and promoting various cellular processes. Despite the unclear necessity of platelet activation, PRP's effectiveness was observed even with low growth factor concentrations. Clinical trials indicated that different PRP preparations could yield varying results in hair growth, suggesting that factors beyond growth factor concentration influenced outcomes. PRP also upregulated signaling pathways and proteins involved in hair growth and prolonged the anagen phase.
5 citations,
January 2013 in “Otorhinolaryngology clinics : an international journal” Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.
5 citations,
September 2019 in “ACS Applied Bio Materials” The hydrogel with bioactive factors improves skin healing and regeneration.
2 citations,
September 2022 in “Journal of trace elements in medicine and biology” Sodium pentaborate pentahydrate can increase hair growth and improve hair quality at certain doses.
2 citations,
December 2019 in “Nanoscience and Nanotechnology Letters” The study investigated the mechanisms by which stromal vascular fraction (SVF) and platelet-rich plasma (PRP) promote hair growth in androgenetic alopecia (AGA). Using in vitro and in vivo models, it was found that both SVF and PRP significantly increased hair growth, with SVF showing superior results. Analysis revealed that SVF and PRP upregulated the expression of anti-apoptotic genes and induced hair follicle cell proliferation. Enzyme-linked immunosorbent assay (ELISA) results indicated that SVF and PRP enhanced the expression of proteins associated with the Wnt/β-catenin signaling pathway, including VEGF and PDGF, thereby promoting hair growth. The effects of SVF were statistically stronger than those of PRP (P < 0.05).
1 citations,
July 2023 in “International Journal of Molecular Sciences” Treating fat stem cells with low oxygen boosts hair growth cell growth through specific signaling pathways.
1 citations,
January 2023 in “Journal of research in pharmacy” Carduus adpressus extract has strong antibacterial, antioxidant, and wound-healing effects.
February 2024 in “Journal of dermatology” CGF therapy may help hair regrowth and improve scars in DLE patients.
Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.
June 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” Platelet-rich plasma (PRP) is a promising treatment for androgenetic alopecia (AGA) due to its high concentration of growth factors and bioactive molecules that aid in tissue repair and wound healing. PRP stimulates hair growth and regeneration by releasing growth factors such as PDGF, TGF-β, VEGF, and IGF, which promote cell proliferation, activate dormant hair follicles, and induce hair cycle growth. Additionally, PRP reduces inflammation, promotes angiogenesis, and may inhibit 5-alpha reductase activity, contributing to its effectiveness in treating AGA. Understanding these mechanisms allows for the optimization of PRP in hair restoration therapies.
February 2023 in “Laboratory Animal Research” Cudrania tricuspidata and Sargassum fusiforme extracts improved hair growth in mice by affecting growth-related genes.
April 2022 in “The Egyptian Journal of Hospital Medicine” Platelet Rich Fibrin improves healing and reduces acne scars by slowly releasing growth factors.
January 2022 in “Springer eBooks” Combining PRP with lipofilling shows promise for tissue regeneration but needs more clinical trials to confirm benefits.
September 2021 in “VNU Journal of Science: Medical and Pharmaceutical Sciences” Platelet-rich plasma, which has growth factors, is used in many medical fields and can promote tissue repair, stimulate hair growth, and increase hair density.
January 2019 in “Springer eBooks” PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
January 2016 in “Más dermatología” Platelet-rich plasma therapy helps heal skin ulcers and stimulates hair growth in dermatology.
November 2014 in “Surgical research updates” Platelet Rich Plasma (PRP) may improve hair transplant success by increasing blood vessel and hair follicle growth.
January 2013 in “Otorhinolaryngology clinics : an international journal” PRP shows promise for improving healing and hair growth in cosmetic surgery but results can vary.
July 2024 in “Experimental Dermatology” AP collagen peptides help hair grow and improve hair health.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
July 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.