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This study found that injecting PDGF-AA and -BB into mouse skin immediately triggered the hair growth cycle's anagen phase, suggesting potential treatment options for certain types of alopecia.

In this study, IGF-I was shown to enhance human hair follicle growth, maintain the anagen phase, and increase expression of certain growth factors and anti-apoptotic markers.

This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.

This study found that mesenchymal stem cells from adipose tissue and hair follicles have a similar ability to differentiate into neurons, which could aid in developing therapies for neurological diseases.

IGF-I helps hair growth by preventing cell death and boosting growth factors.

This study found that Pdgfα signaling is crucial for maintaining dermal adipose tissue in mice by initiating dermal adipocyte stem cell proliferation, with implications for age-related skin defects.

This study found that PDGF-D acts as a potent mitogenic factor in adipose-derived stem cells, enhancing their proliferation, migration, and growth factor expression, suggesting its use as a preconditioning agent for ASC transplantation.

This study found that in a fluconazole-induced alopecia-like rat model, a 14-day treatment with hypoxia-induced mesenchymal stem cell exosomes significantly increased TGF-β and PDGF levels, which may improve hair growth and suggests a potential therapeutic strategy for alopecia and other inflammation-related skin disorders.

In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.

This study found that PDGFA is critical for the proliferation and maintenance of adipocyte stem cells in skin but not other white adipose tissues, highlighting unique regulatory mechanisms in different tissue depots.

This study suggests that PDGFA and BMP2 play a role in the hair follicle cycle in cashmere goats, with PDGFA particularly involved in activating the growth phase.

LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.

In this study, secretomes from hypoxic mesenchymal stem cells were found to increase PDGF and reduce IL-1β gene expression in rats, potentially offering an effective topical treatment for alopecia caused by long-term fluconazole use.

This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.

The researchers found that melatonin implantation in Cashmere goats influenced PDGFA gene expression and hair growth cycles, indicating it may control hair phase transformation from growth to catagen and telogen.

In this study conducted on rabbits, conventional blood treated with 120% sodium citrate was observed to achieve the highest platelet recovery and enrichment coefficient, while altering sodium citrate concentrate affected levels of growth factors PDGF and TGF-β1 after plasma activation.

This review summarizes existing literature on PDGF's role in adipose-derived stem cells, highlighting PDGFRβ's functions in inhibiting white adipocyte differentiation and promoting proliferation and angiogenesis.

This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.

This study found that platelet-rich plasma significantly increased hair count, density, and the percentage of anagen hairs in patients with androgenetic alopecia, but these improvements did not correlate with platelet or growth factor levels.

In this study, researchers found that certain cytokines can significantly down-regulate PDGF expression in dermal papilla cells and follicular keratinocytes, indicating a potential link between PDGF signaling and catagen induction.

This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.

This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.

In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.

This study observed that adipose-derived stem cells modified with trichogenic factors have similar properties to dermal papilla cells and show enhanced hair regeneration potential compared to unmodified adipose-derived stem cells.

This case report presents the first documented instance of basal cell carcinoma and cutaneous leiomyosarcoma occurring as a collision neoplasm in the same biopsy specimen.

The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.

This study found that stimulating dermal papilla cells with specific adipo-osteogenic factors and growth factors helped maintain their viability and restored their hair-forming activity in vitro.

PRP preparation partially activates platelets, causing varied growth factor release.

In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.

This study suggests that APC collagen peptides may accelerate hair growth and promote overall hair health by enhancing cellular proliferation and activating specific signaling pathways in human and mouse models.