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This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by modulating key signaling pathways, suggesting a novel therapeutic approach for degenerative diseases.

This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.

This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.

This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This review discusses the potential of mesenchymal stem cells and their secretome, mainly extracellular vesicles, in Parkinson's disease therapy, highlighting their neuroprotective abilities and therapeutic prospects, but it reports no clinical results.

This review evaluates existing preclinical and clinical studies on stromal vascular fraction for treating male sexual dysfunction, finding limited data and emphasizing the need for more research before conducting clinical trials.

This study found that human umbilical cord blood mesenchymal stem cells promoted hair growth by advancing anagen onset and increasing hair follicle regeneration in an in vivo model.

This study found that exosomes derived from hypoxia-conditioned mesenchymal stem cells modulated inflammatory biomarkers by decreasing CXCL12 and increasing IL-10 expression in a DHT-induced androgenic alopecia mouse model, indicating potential for treating hair loss through immunoregulation.

This study found that human platelet lysate supported mesenchymal stem cell growth as effectively as fetal bovine serum, while fetal bovine serum was more effective for hepatocyte proliferation.

This study found that mesenchymal stem cells from chronically inflamed human livers maintain their key cellular characteristics, supporting their potential use in developing liver cell therapies.

This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.

This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.

This study found that combining ISX-9 with mesenchymal stem cells enhanced their ability to reduce inflammation and repair lung damage in an acute lung injury model compared to using the cells alone.

This review discusses the therapeutic potential of MSC-derived secretomes for treating degenerative and inflammatory diseases, reporting no new clinical results but highlighting their proposed mechanisms and advantages over direct MSC transplantation.

This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.

This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.

This study found that medium/large extracellular vesicles derived from hair follicle and adipose tissue mesenchymal stromal cells both demonstrated significant neuroprotective and anti-inflammatory effects in cell cultures, highlighting their potential use as biopharmaceuticals for treating neurodegenerative diseases.

In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.

In this study, human hair follicle-derived mesenchymal stem cells promoted Achilles tendon repair in rabbits by upregulating collagen types I and III, suggesting potential as a treatment for tendinopathy.

This review discusses how using hydrogels as a three-dimensional culture platform for mesenchymal stem cells might affect the production of extracellular vesicles, highlighting challenges in standardization and opportunities to boost EV yield via combined hydrogels and bioreactor methods.

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.

This review discusses various types of stem cells used in regenerative medicine, including adult stem cells and induced pluripotent stem cells (iPSCs), and evaluates them based on their embryonic tissue origins to explore new therapeutic approaches.

This study reviews various factors affecting mesenchymal stem cell transplantation efficacy, including platelet concentrate composition, donor characteristics, and environmental influences, and examines strategies for optimizing outcomes through preconditioning and combined therapies in regenerative medicine.

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

This review highlights the lack of a comprehensive synthesis of stem cell therapy research by categorizing current studies according to medical specialty and stem cell type, while analyzing their advantages and limitations across various medical disciplines.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.

This review explores the current and experimental therapies for chronic wounds, emphasizing the potential of cellular and immunotherapies in addressing these persistent conditions, but notes a shortage of comprehensive studies on their effectiveness.