1 citations
,
May 2017 in “Journal of cosmetic and laser therapy” This study found that lasers and light devices may alleviate recalcitrant skin side effects in cancer patients treated with EGFR inhibitors, offering an alternative for those who do not respond to traditional therapies.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” This study found that cilostazol promoted hair growth in human dermal papilla cells and mouse models, suggesting its potential as a therapeutic target for alopecia treatment.
1 citations
,
August 2016 in “Dermatology - Open Journal” In this study, the researchers found that optic atrophy 1 (OPA1) is involved in the transition between filamentous and rounded mitochondria in hair follicle dermal papilla cells, potentially influencing cellular energy dynamics.
1 citations
,
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
1 citations
,
January 2015 in “Sexual Medicine Reviews” This review discusses the management of recurrent ischemic priapism, highlighting that various treatments show differing efficacy and side effect profiles but that more research is needed to refine these strategies.
1 citations
,
January 2007 in “Side effects of drugs annual” This chapter reviews dermatological treatments, noting that botulinum toxin A is associated with a higher occurrence of focal weakness compared to controls, and reports on adverse effects of finasteride and PUVA therapy.
January 2026 in “Andrology” This study found that PRP injections are safe and may slightly reduce penile curvature and improve PDQ scores in men with stable-phase Peyronie's Disease, but the changes are not significant enough to predict long-term effects.
October 2025 in “Pediatric Dermatology” This report describes how ultraviolet-induced fluorescence dermoscopy helped accurately diagnose scalp disorders, specifically alopecia areata and tinea capitis, in pediatric patients.
July 2023 in “Clinical, cosmetic and investigational dermatology” In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.
In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.
April 2016 in “Journal of Investigative Dermatology” This study found that the peptide derivative beta-Ala-Pro-Dab-NHbenzyl may reduce wrinkles and sebum production in human skin by inhibiting dipeptidyl peptidase 4, suggesting potential for acne and skin inflammation treatment.
January 2025 in “Recent Patents on Anti-Cancer Drug Discovery” In this study, neoadjuvant treatment with durvalumab combined with albumin-bound paclitaxel and carboplatin in patients with driver gene-negative stage III NSCLC showed a 65% objective response rate and was associated with high pathological response rates and improved immune function, with most adverse events being mild.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
July 2024 in “Research Square (Research Square)” In this study, researchers identified that certain inflammatory cytokines, including osteoprotegerin and leukemia inhibitory factor, are inversely associated with hypertrophic scar risk, whereas others like CDCP1, GDNF, and PD-L1 show a positive association, suggesting potential pathways for intervention in scar formation.
This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.
This study observed two distinct groups of alopecia areata lesions based on PD-1 expression in T cells from biopsied skin samples, suggesting potential differences in subtypes or stages of the disease that warrant further investigation.
April 2023 in “Journal of Investigative Dermatology” This study found that in biopsied skin samples of alopecia areata, a lower anagen/telogen ratio was associated with increased T cell infiltration, and enhancing the PD-1/PD-L1 axis may inhibit CD8+T cell infiltration and improve the condition.
May 2022 in “Голова и шея.” This report describes a case of a patient with metastatic renal cell carcinoma who developed a psoriasiform skin lesion while undergoing immune checkpoint inhibitor therapy.
May 2022 in “Benha Journal of Applied Sciences” This study found that programmed death-ligand 1 (PD-L1) levels correlated with the severity of alopecia areata, suggesting its potential as an indicator and possible target for new treatments.
September 2020 in “Research Square (Research Square)” This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by modulating key signaling pathways, suggesting a novel therapeutic approach for degenerative diseases.
August 2020 in “Research Square (Research Square)” This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.
This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.
January 2004 in “Zhōnghuá yàoxué zázhì” This study successfully synthesized finasteride using a method that avoids expensive reagents and column chromatography, achieving a higher yield than previously reported.
July 2026 in “Pharmaceuticals” This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.
March 2026 in “Research Square” This study developed a novel regenerative platform using nanozyme-enabled materials combined with exosomes and laser stimulation to enhance wound healing in a mouse model, which more effectively regulated reactive oxygen species and improved early angiogenesis and collagen organization compared to conventional methods.
November 2025 in “Biomedicines” In this review, researchers reported that pyroptosis, a type of inflammatory cell death linked to inflammasome activity, is a key factor in the pathogenesis of alopecia areata and may present new therapeutic opportunities, though most treatments are still in early research stages.
March 2024 in “Ukraïnsʹkij vìsnik psihonevrologìï” This study found that among women with diffuse alopecia, 47.7% exhibited psychopathological symptoms, with mixed alopecia patients showing more severe manifestations compared to those with metabolic alopecia, suggesting the need for personalized management strategies.
September 2026 in “Russian Journal of Skin and Venereal Diseases” In this study, photodynamic therapy combined with platelet-rich plasma showed potential for greater efficacy than photodynamic therapy alone in treating androgenic alopecia, with both approaches improving hair density without serious side effects.
August 2026 in “Materials & Design” This study developed a multifunctional 3D-printed hydrogel scaffold, SH-EGCG, that showed promising results for repairing infected diabetic wounds; in lab and animal tests, it demonstrated antibacterial activity, enhanced wound healing, and improved tissue regeneration and remodeling through various supportive mechanisms.
August 2026 in “Russian Journal of Skin and Venereal Diseases” In this prospective study, combining photodynamic therapy with PRP therapy significantly improved hair growth, quality of hair, and quality of life in women with acute telogen effluvium, compared to using each therapy alone.