4 citations
,
March 2014 in “The FASEB Journal” This study observed that deleting ARNT in keratinocytes of mice reduced zigzag hair production and altered hair follicle differentiation, likely by affecting the expression of specific cyclin-dependent kinase inhibitors.
3 citations
,
January 2018 in “Methods in molecular biology” This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.
1 citations
,
November 2015 in “Indian Journal of Clinical Biochemistry” The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
1 citations
,
July 2013 in “Hair transplant forum international” This abstract lacks results; it aims to understand hair follicle regulation mechanisms but does not report specific findings or data.
November 2023 in “Food science of animal resources” This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.
September 2022 in “Institutional Repositories DataBase (IRDB)” Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.
December 2013 in “Research Portal (King's College London)” This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.
42 citations
,
August 1999 in “The American journal of pathology” This study found that basal cell carcinomas show strong expression of vitamin D receptors at both mRNA and protein levels, suggesting a potential role in tumor growth regulation.
23 citations
,
May 2009 in “International Journal of Dermatology” In this study, no association was found between the AR gene and type II androgenetic alopecia in Egyptian women, suggesting it is not a useful biomarker for predisposition.
15 citations
,
April 2003 in “Journal of Dermatological Science” This study found no significant associations between the polymorphisms of SRD5A1 and SRD5A2 genes and androgenetic alopecia, clinical types of baldness, or response to finasteride in Koreans.
12 citations
,
June 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” This case study reported a rare infection by Trichosporon inkin, causing white piedra in a family in Southern Brazil, emphasizing the importance of molecular tools for precise identification.
4 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
January 2006 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study found that Rubus coreanum extract promotes hair growth in mice, but its effects are not due to inhibition of specific enzymatic activities or growth factor expression.
25 citations
,
August 2006 in “Human Reproduction” This study found that the GGC repeat length significantly influenced testosterone levels in oral contraceptive users from high-risk breast cancer families, and homozygosity for short alleles may be linked to increased breast cancer risk.
2 citations
,
July 2011 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” This study identified genetic variations in the DSG4 gene among sheep, revealing valuable markers for assessing their impact on wool traits.
349 citations
,
January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
222 citations
,
January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
199 citations
,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
186 citations
,
July 1998 in “Journal of Cutaneous Medicine and Surgery” This study found that shorter CAG-repeat lengths in the androgen receptor may be associated with the development of androgen-mediated skin disorders like androgenetic alopecia, acne, and hirsutism in both men and women.
140 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that mice lacking the 1αOHase enzyme, which is responsible for producing a key vitamin D metabolite, showed impaired epidermal differentiation and delayed recovery of skin barrier function after disruption.
136 citations
,
June 2006 in “Journal of Dermatological Science” This study found that injecting PDGF-AA and -BB into mouse skin immediately triggered the hair growth cycle's anagen phase, suggesting potential treatment options for certain types of alopecia.
122 citations
,
July 2005 in “The FASEB journal” This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.
108 citations
,
July 2004 in “American Journal of Pathology” This study suggests that nerve growth factor plays a crucial role in the stress-induced termination of hair growth in mice, and its antagonism might offer a therapeutic approach to mitigate stress-related hair loss.
104 citations
,
October 2016 in “PLoS ONE” This study found that CRISPR/Cas9-mediated disruption of the FGF5 gene in goats increased hair follicle numbers and fiber length, suggesting more cashmere production could be achieved.
104 citations
,
May 2003 in “Endocrinology” This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.
98 citations
,
April 1997 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively blocks rat enzymes, but with varying methods and strength.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” This study found that the retinoid all-trans retinoic acid induced a catagen-like stage in human scalp hair follicles, suggesting upregulation of TGF-beta2 as a contributing mechanism.
84 citations
,
July 2003 in “European journal of biochemistry” This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.
81 citations
,
January 2006 in “Journal of cellular physiology” This study found that the absence of the vitamin D receptor disrupts hair follicle structure during the first catagen in mice, linked to increased expression of the hairless gene.