research The Role of Astrotactin2 in Regulating Mammalian Skin Polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
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research Planar Cell Polarity Effector Gene Intu Regulates Cell Fate-Specific Differentiation of Keratinocytes Through the Primary Cilia
Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
research Functional Redundancy of Frizzled 3 and Frizzled 6 in Planar Cell Polarity Control of Mouse Hair Follicles
Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
research Responses of Hair Follicle–Associated Structures to Loss of Planar Cell Polarity Signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Celsr1 And Celsr2 Exhibit Distinct Adhesive Interactions And Contributions To Planar Cell Polarity
Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice
Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
research Region-Specific Reversal of Epidermal Planar Polarity in the Rosette Fancy Mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Whole Blood Transcriptome Profiling Identifies Candidate Genes Associated With Alopecia in Male Giant Pandas
Researchers found genes linked to hair loss in male giant pandas.
research Wnt5a Suppresses β-Catenin Signaling During Hair Follicle Regeneration
Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
research Wound Healing in Development: Mechanisms and Regulation
Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
research Recent Updates on Wnt Signaling Modulators: A Patent Review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration
WNT signaling is crucial for skin development and healing.
research Molecular Signaling and Nutritional Regulation in the Context of Poultry Feather Growth and Regeneration
Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.
research Promoting Axonal Regeneration Through Exosomes: An Update of Recent Findings on Exosomal PTEN and mTOR Modifiers
Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
research Cell Polarization Defects in Early Heart Development
Defects in certain proteins cause major heart abnormalities during early development.
research Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis
The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
research The Role of R-Spondins and Their Receptors in Bone Metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research Fzd2 Controls Multiple Aspects of Epidermal Development Through Distinct Signaling Mechanisms
Fzd2 is important for skin and hair development through various signaling ways.
research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
research When Whorls Collide: The Development of Hair Patterns in Frizzled 6 Mutant Mice
Hair follicles in mutant mice self-organize into ordered patterns within a week.
research Order From Disorder: Self-Organization In Mammalian Hair Patterning
Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
research Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
research Cleave But Not Leave: Astrotactin Proteins in Development and Disease
Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.
research Dynamic Wnt5a Expression in Murine Hair Follicle Cycle and Its Inhibitory Effects on Follicular Growth
Wnt5a may slow down hair growth in mice.