6 citations
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September 2024 in “Journal of Clinical Medicine” This review explored the relationship between autoimmune thyroiditis and various autoimmune skin conditions, highlighting shared genetic markers and immunological mechanisms, such as disrupted immune tolerance and oxidative stress, which may contribute to the development of these disorders.
February 2023 in “Materials today bio” In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.
February 2024 in “International journal of molecular sciences” This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.
89 citations
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May 1999 in “Pediatric Dermatology” This article reviews the treatment options for tinea capitis, suggesting that itraconazole, terbinafine, and fluconazole are effective and safe alternatives to griseofulvin but reports no new clinical results.
49 citations
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November 2022 in “Life” This review discusses global variations in polycystic ovary syndrome prevalence and highlights the need for more comprehensive studies to understand its association with race, ethnicity, and diagnosis criteria; it reports no new results.
37 citations
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October 2021 in “Nutrients” This study discusses the potential association between low vitamin D levels and insulin resistance, suggesting that vitamin D deficiency may contribute to disorders like obesity and diabetes, but emphasizes the need for further research to confirm these links.
35 citations
,
February 2024 in “Science Advances” This study introduces a magnet-assisted fabrication strategy for creating complex 3D soft bioscaffolds, demonstrating its effectiveness by producing structures with overhangs and supporting biohybrid actuators, promising advancements in biomedical applications.
24 citations
,
July 2021 in “Pharmaceutics” This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
16 citations
,
November 2021 in “Antioxidants” This review examines the role of oxidative stress in male hypogonadism associated with noncommunicable chronic diseases and discusses various management strategies, but it presents no new clinical findings.
7 citations
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March 2023 in “Antioxidants” This study confirmed the antioxidant role of rosemary, suggesting its potential use in treating inflammatory and infectious skin conditions, but emphasizes that more large-scale controlled trials are necessary to fully understand its clinical impact.
5 citations
,
February 2022 in “Seminars in cell & developmental biology” This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” This study found that subthermal CRET treatment increased keratinocyte proliferation and modulated cytokine production, affecting the inflammatory response in human keratinocytes through EGFR and ERK1/2/NF-κB pathways.
2 citations
,
June 2025 in “International Journal of Molecular Sciences” In this study, Carthamus caeruleus root juice exhibited in vitro anti-inflammatory effects by stabilizing human erythrocyte membranes and inhibiting albumin denaturation, as well as showing potential inhibition of COX-2 through in silico analysis; however, further research is needed to confirm efficacy and mechanisms.
1 citations
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July 2025 in “Cosmetics” This review highlights the multifunctional benefits of plant-derived ingredients in skincare, such as antioxidant and anti-inflammatory effects, supported by biological evidence from medicinal plants like Camellia sinensis and Panax ginseng, suggesting their potential as natural dermocosmetic agents.
1 citations
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January 2023 in “International journal of molecular sciences” This study found that S. scabiei infestation in rabbits leads to epidermal thickening possibly due to apoptosis-related proliferation and keratinization of the skin.
1 citations
,
January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
May 2023 in “Health science reports” This review discusses the harmful effects of coloring shampoos containing trihydroxybenzene on the scalp-skin barrier and emphasizes the need for safer ingredient selection to prevent side effects.
Developing microRNA-based treatments is hard but has potential.
37 citations
,
January 2005 in “Clinics in dermatology” This review discusses recent advances in understanding the genetics of hair and nail disorders and reports no new clinical results.
8 citations
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December 2003 in “Experimental Dermatology” In this study, injecting chimeric RNA–DNA oligonucleotides into mice skin caused a temporary mutation in keratin 17, altering hair morphology, but the mutation was transient due to genetic compensation or cell replacement.
188 citations
,
January 2022 in “PubMed” This review discusses recent advancements in congenital adrenal hyperplasia research, including improved diagnostic techniques, alternative treatments, and insights from long-term outcome data, but it reports no new clinical results.
108 citations
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January 2003 in “Fertility and Sterility” This study found that flutamide at 250 mg daily modestly improved hair thinning in premenopausal women with hyperandrogenic alopecia over one year, while cyproterone acetate and finasteride were not effective.
76 citations
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July 2009 in “Neuroscience” This study found that inhibiting allopregnanolone synthesis in late gestation fetal sheep increased apoptosis and dead cell count in the hippocampus and cerebellum, effects that were mitigated by alfaxalone co-infusion.
37 citations
,
January 2023 in “Ophthalmology and Therapy” In this study, more than 25% of children experienced axial length shortening greater than 0.05 mm/year following repeated low-level red-light therapy.
29 citations
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September 2004 in “Fertility and Sterility” This study found that an intermittent low-dose regimen of finasteride (2.5 mg every 3 days) effectively reduced hirsutism scores in women with idiopathic hirsutism or polycystic ovary syndrome, with fewer side effects than continuous daily administration.
21 citations
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April 2016 in “International Journal of Oncology” This study found that treatment with the GnRH agonist Triptorelin significantly decreased invasion and expression of S100A4 and CYR61 in certain breast cancer cells, suggesting a potential role in slowing cancer progression.
16 citations
,
August 2021 in “Tumor Biology” This review discusses the dual role of the TMPRSS2 gene in coronaviral lung infection and prostate cancer, cautioning against TMPRSS2 inhibitors for early prostate cancer due to potential pro-inflammatory effects.
6 citations
,
January 2024 in “Cancers” This systematic review found that antiandrogens do not appear to protect against SARS-CoV-2 infection or reduce COVID-19 severity, suggesting their use is not advisable for COVID-19 treatment.
5 citations
,
May 2022 in “Clinical & Experimental Metastasis” This study found that minoxidil and ranolazine, individually and in combination, reduced cellular invasiveness in hypoxic triple-negative breast cancer cell lines, suggesting potential anti-metastatic effects at clinically relevant doses.