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This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.

This study found that thyroxine modulates peripheral molecular clock gene expression in human hair follicles, which may have implications for treating clock-related diseases in patients with thyroid dysfunction.

This study found that 3% peppermint oil significantly enhanced hair growth in C57BL/6 mice, showing increased dermal thickness, follicle number, and follicle depth compared to other treatments.

This study found that BAF200, a subunit of the PBAF chromatin remodeling complex, is crucial for heart development and coronary artery formation in mice, as its absence led to embryonic lethality with severe cardiac defects.

This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.

This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

This study suggests that adipose-derived mesenchymal stem cells from diabetic mice can enhance wound healing by promoting fibroblast growth, migration, angiogenesis, and differentiation into fibroblasts and endothelial cells.

In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.

In this study, Treg depletion impaired skin wound healing in mice, potentially by altering the cytokine environment and expanding certain T-cell populations, disrupting the normal healing process.

This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.

This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.

This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.

This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.

In this study, Meis1 was found to regulate epidermal homeostasis and act as a proto-oncogenic factor in skin tissues, with differences in expression patterns between normal and tumor cells.

This study suggests that inactivation of β-catenin is necessary for chick retina regeneration, as it allows cells to enter the cell cycle during injury and promotes regeneration without needing FGF2.

This study reported that nanoemulsions significantly improved the skin permeability of thiocolchicoside compared to its aqueous solution, suggesting they are effective carriers for its transdermal delivery.

This study found that Merkel cell clusters require Frizzled6 signaling for their polarity information, while other hair follicle-associated structures align their orientation based on the hair follicle itself.

This study found that Wnt10b promotes melanocyte maturation and pigmentation in the hair bulbs of mice by activating canonical Wnt signaling.

Eating isoflavone can help mice grow hair by increasing a growth factor.

This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.

This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.

In this study, microneedles combined with finasteride nanostructured lipid carriers (FIN-NLC-MNs) were found to enhance skin penetration and specifically target hair follicles, promoting hair growth and gene regulation in androgenetic alopecia.

This study found that ginsenoside Rb1 promoted the growth of mink hair follicles and dermal papilla cells, potentially through activating the PI3K/AKT/GSK-3β signaling pathway.

This study found that the PLC2 gene plays a critical role in auxin-mediated root development in Arabidopsis, influencing root growth and PIN2 distribution.

This study found that exercise decreases the expression of 5αR1, thereby enhancing the PI3K/AKT signaling pathway in PCOS rats.

This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.

This source reports that thymosin beta 4 accelerated dermal wound repair in phase 2 clinical trials for pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds and was well tolerated.

This review examines cell-based therapies for limbal stem cell deficiency, highlighting epidermal and hair follicle-derived stem cells as promising candidates for future clinical trials, but reports no new clinical findings.