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This study demonstrates that bulge KSCs from hair follicles can transdifferentiate into corneal epithelial-like cells under specific conditions, which could support bioengineered cornea development.

This study found that murine vibrissa hair follicle stem cells can be differentiated into corneal epithelial-like cells in vitro using limbus-specific microenvironmental factors, suggesting a potential therapeutic source for ocular surface disorders.

This study found that differentiated cells of the corneal epithelium can be converted to hair and interfollicular epidermis through a multistep process involving dermal developmental signals.

This study explored the molecular mechanisms determining the identity of keratinocytes and corneal epithelial cells, finding that miRNAs from the Gtl2-Dio3 region, which regulate key signaling pathways, play a significant role in cell identity through the Hox/Gtl2-Dio3 miRNA axis.

This study found that the corneal epithelium differentiation program can proceed independently of lens formation, suggesting the corneal program is the default in eye development.

This review highlights the roles of key transcription factors and signaling pathways in regulating olfactory epithelium regeneration, discussing recent advances in single-cell and spatial transcriptomics as well as organoid models to enhance understanding of olfactory regeneration mechanisms.

This study integrated single-cell RNA-seq data from four previous studies to create a comprehensive human corneal cell state meta-atlas, revealing novel marker genes, rare cell states, and distinct transcription factors, and offering a tool to enhance future cornea research.

This study developed rat monoclonal antibodies that specifically detect Pax1/PAX1 protein, which could improve diagnostic protocols for conditions involving deregulated Pax1/PAX1 expression.

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.

The Paxbp1 gene is crucial for healthy hair follicles.

This study found a novel PAX9 gene mutation that may cause tooth agenesis and trichodysplasia in a studied family.

This study found that Hex gene expression patterns in chick embryo dorsal skin during feather bud development suggest a significant role in initiating feather morphogenesis.

This review discusses the roles of PAX3 in melanocyte development and melanoma progression but reports no new experimental results; the authors propose it as a key regulatory factor and call for further investigation.

This study found that paxillin knockdown in human granulosa-derived cells and mouse models decreased androgen receptor protein levels and altered gene expression, suggesting paxillin's role in protecting against androgen excess effects, as observed in a polycystic ovary syndrome mouse model.

This study identified a genetic locus associated with idiopathic scoliosis in females, which might influence spinal gene expression and was previously linked to protection from early-onset alopecia.

This study found that in early retinal neurogenesis in mice, the transcription factor Lhx2 regulates Sonic Hedgehog signaling by controlling expression of pathway genes like the co-receptors Gas1 and Cdon.

This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.

This study suggests that egfl6 expression in the pharyngeal pouches is not essential for craniofacial development in zebrafish.

This study found that the transcription factor Lhx2 regulates Sonic Hedgehog signaling in mouse retinal progenitor cells, mainly by controlling the expression of co-receptors essential for effective pathway activation during early retinal neurogenesis.

This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This study indicates that the Sp6 gene is crucial for the development of skin, teeth, limbs, and lungs in mice, possibly through regulating apoptosis.

This study found that misexpression of Hoxc8 in mice led to ectopic mammary development and suggests Hox genes may play crucial roles in the regional specification and initiation of cutaneous accessory organs.

This study found that endothelial cells under serum deprivation significantly upregulated genes related to inflammation and coagulation, which may impact outcomes in tissue transfer procedures.

This study found that Polycomb repressive complex 1 is crucial for skin development and stem cell specification, influencing gene activity beyond its known repressor functions.

This study found that the Lim-homeodomain transcription factor Lhx2 regulates Sonic Hedgehog signaling during early retinal neurogenesis in mice by controlling the expression of pathway genes in retinal progenitor cells.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.