26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
26 citations
,
September 2015 in “Journal of The American Academy of Dermatology” In this study, spironolactone was reported to stabilize or improve female pattern hair loss in 74.3% of treated women, especially those with signs of hyperandrogenism.
26 citations
,
April 2009 in “Australasian Journal of Dermatology” In this study, a 9-year-old girl with female pattern hair loss showed clinical improvement and hair regrowth after six months of daily oral spironolactone.
25 citations
,
June 2018 in “Clinical and Experimental Dermatology” This study found that combining fractional radiofrequency microneedling with 5% topical minoxidil improved hair count and thickness more than minoxidil alone in Chinese men with male pattern hair loss.
25 citations
,
July 2013 in “Journal of Dermatological Science” This study suggests that the androgen receptor locus on the X chromosome may play a role in the pathogenesis of early-onset female pattern hair loss.
25 citations
,
January 1998 in “Dermatology” Male pattern hair loss negatively affects quality of life, but drug treatments can help.
24 citations
,
December 2011 in “Journal of The American Academy of Dermatology” This study found that Caucasian female hair is denser than Asian female hair in the occipital region regardless of treatment but thinner in diameter in both the frontal and occipital regions.
23 citations
,
January 2016 in “International Journal of Trichology” This study found that women with female pattern hair loss had significantly lower serum Vitamin D3 levels compared to healthy controls.
23 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews the pathophysiology, diagnosis, and treatment of female pattern hair loss, highlighting the importance of early medical intervention to arrest hair loss progression, but reports no new clinical results.
22 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
22 citations
,
May 2013 in “Experimental and Therapeutic Medicine” This study found that topical minoxidil improved the quality of life in female patients with pattern hair loss.
21 citations
,
November 2017 in “Archives of Dermatological Research” This study found that women with female pattern hair loss had increased 5α-reductase isozymes and decreased aromatase mRNA levels, potentially affecting their response to treatment.
21 citations
,
February 2017 in “International Journal of Women's Dermatology” This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
21 citations
,
April 2016 in “International Journal of Dermatology” This study found a significant association between female pattern hair loss and metabolic syndrome in Egyptian women, with waist circumference and hypertension particularly linked to the severity of hair loss.
21 citations
,
December 2013 in “Archives of Dermatological Research” No link found between new male baldness genes and female hair loss.
21 citations
,
August 2013 in “Journal of Dermatological Treatment” This review discusses the mixed evidence and high risk of bias in studies on low-level light therapy for treating androgenetic alopecia and calls for rigorous randomized controlled trials to assess its efficacy.
21 citations
,
January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
21 citations
,
January 2007 in “Australasian Journal of Dermatology” This case report describes how a 53-year-old woman with female pattern hair loss experienced further hair regrowth when topical minoxidil was added to her spironolactone treatment after initial results plateaued.
20 citations
,
December 2008 in “PubMed” In this study, treatment with finasteride 1 mg/day for five years significantly reduced the likelihood of further visible hair loss in men with androgenetic alopecia compared to placebo.
19 citations
,
August 2000 in “International Journal of Dermatology” This article discusses the medical management of male pattern hair loss and reports no new clinical findings.
18 citations
,
February 2012 in “Experimental Dermatology” This study found no significant association between selected gene variants and female pattern hair loss, suggesting these genes might not be involved in its development.
17 citations
,
July 2003 in “Metabolism-clinical and Experimental” This study found that young women with female-pattern hair loss exhibit increased testosterone production rates while dihydrotestosterone production rates remain within or below the normal range.
16 citations
,
May 2020 in “Journal of The European Academy of Dermatology and Venereology” This publication involves a case-series report on the treatment of male and female pattern hair loss using sublingual minoxidil in 64 patients, but it does not include an abstract or results.
16 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This abstract discusses the efficacy of spironolactone, cyproterone acetate, and flutamide in treating female pattern hair loss, noting that flutamide use requires caution due to potential liver toxicity, especially at high doses.
16 citations
,
June 2008 in “Springer eBooks” Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
15 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the pathophysiology, diagnosis, systemic associations, and treatments for female pattern hair loss and reports no new clinical findings.
15 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This article notes the lack of physician-reported outcome studies supporting the efficacy of off-label spironolactone in treating female pattern hair loss, despite its common prescription alongside FDA-approved topical minoxidil.
15 citations
,
February 2018 in “Journal of Cosmetic and Laser Therapy” This study observed hair regrowth and increased density in four cases of androgenetic alopecia treated with a non-ablative erbium glass fractional laser and topical finasteride, with no significant side effects reported.
15 citations
,
January 2017 in “JAMA Dermatology” This study found that topical minoxidil improved female pattern hair loss, finasteride was not more effective than placebo, and laser devices showed inconsistent results but increased hair count compared to baseline.