December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Topical finasteride is promising for hair loss with minimal side effects but needs more research and approval.
December 2021 in “Skin appendage disorders” This study developed and validated an objective dermoscopic severity score for evaluating female pattern hair loss, which may serve as a supplementary outcome measure in therapeutic trials.
December 2021 in “IP Indian journal of clinical and experimental dermatology” In this study, trichoscopy was identified as a useful non-invasive tool to aid in the diagnosis of female pattern hair loss, with peri pilar sign and hair diameter variability being common findings.
November 2021 in “Journal of The American Academy of Dermatology” This study found that advanced stages of female pattern hair loss are associated with increased age, menopausal state, and hypertension, while acne vulgaris is more prevalent in earlier stages.
October 2021 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this hospital-based cross-sectional study, researchers observed that trichoscopy effectively differentiates between severe and mild male pattern hair loss by identifying specific features such as yellow and white dots, vellus hair, and hair shaft diversity.
October 2021 in “Journal of Investigative Dermatology” In this study, the researchers found that scalp hair follicles affected by female pattern hair loss are poorly vascularized, likely affecting nutrient delivery, but capable of nutrient uptake when supplemented.
October 2021 in “QJM: An International Journal of Medicine” This study found that injection of adipose-derived adult stem cells improved hair density, thickness, and reduced inflammation in women with female pattern hair loss over 24 weeks.
September 2021 in “Journal of advances in medicine and medical research” This study indicated a correlation between female pattern hair loss and decreased serum levels of Vitamin D3, suggesting that Vitamin D3 evaluation may be important in managing this condition.
August 2021 in “Journal of The American Academy of Dermatology” This article discusses the androgenicity of progestins used in hormonal contraceptives and its potential impact on female pattern hair loss, but reports no new clinical findings.
July 2021 in “British Journal of Dermatology” Low testosterone levels may contribute to female pattern hair loss in men.
May 2021 in “Journal of the Endocrine Society” This study found that the severity of female pattern hair loss in premenopausal women was associated with clinical signs of hyperandrogenism, such as hirsutism and acne, but not with biochemical parameters.
April 2021 in “Journal of Investigative Dermatology” This study found that oral spironolactone improved or maintained hair condition in females with scarring alopecia and female pattern hair loss, with 83% of patients tolerating the treatment well, despite some side effects like hyperkalemia and leg cramps.
In this study, a modified Sinclair scale was presented for evaluating hair loss severity in men with female pattern hair loss, outlining stages from normal hair density to severe hair loss while preserving the anterior hairline. Reliability data for using this scale was also included.
January 2021 in “Journal of cosmetology & trichology” In this follow-up study, participants with severe androgenic/estrogenic alopecia showed increased hair growth 10 months after ending vacuum therapy and cosmetic emulsion treatment, highlighting the therapies' potential effectiveness.
January 2021 in “Menoufia Medical Journal” This study found a significant correlation between metabolic syndrome components, particularly waist circumference and hypertension, and female pattern hair loss.
December 2020 in “Journal of The American Academy of Dermatology” In this study, machine learning models showed high accuracy in predicting therapeutic outcomes for female pattern hair loss, highlighting the significant impact of age of onset and condition duration on treatment response.
December 2020 in “The Medical journal of Basrah University” This study observed that Iraqi women with female pattern hair loss had significantly lower serum vitamin D levels compared to healthy controls, suggesting a possible role of vitamin D in the condition's development.
November 2020 in “Acta Scientific Women's Health” In this study of women treated for dermatological conditions in West Midlands, England, low vitamin D levels were significantly linked to hair loss, especially in women aged 35-45, suggesting vitamin D's potential role in prevention and treatment of hair loss in this group.
November 2020 in “Journal of The American Academy of Dermatology” This study observed a high prevalence of PCOS among young female-pattern hair loss patients and suggested that AMH levels might be more indicative of FPHL than traditional androgens.
November 2020 in “International Journal of Research in Dermatology” This study found that minoxidil is the most commonly preferred treatment for mild and severe female pattern hair loss, with PRP often used in combination, but highlights the need for consistent treatment guidelines.
November 2020 in “Skin Research and Technology” This study found that videodermoscopy showed higher sensitivity and specificity than clinical examination for diagnosing female pattern hair loss and may serve as an alternative to scalp biopsy in the future.
November 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This perspective highlights evidence suggesting inflammation plays a significant role in male and female pattern hair loss, indicating that targeting inflammatory pathways may improve future therapeutic options.
In this study, 87% of women with female pattern hair loss experienced hair regrowth and reduced hair fall after six months of treatment with platelet-rich plasma therapy combined with a Derma roller, suggesting it as a safe treatment option.
April 2020 in “Journal of The American Academy of Dermatology” In this study, to address long wait times for alopecia specialists, researchers implemented shared medical appointments for women with female pattern hair loss, modeled on formats previously used for conditions like acne and vitiligo.
January 2020 in “Journal of Clinical Dermatology” This study found that oral dutasteride significantly increased hair density but not thickness in women with female-pattern hair loss, and identified a mechanism involving β-catenin activation.
January 2020 in “Hair transplant forum international” Oral minoxidil helps female hair loss, topical finasteride treats AGA, and sulfotransferase activity predicts minoxidil effectiveness.
January 2020 in “Journal of Clinical Dermatology” This study observed that the proportion of female pattern hair loss among total alopecia cases has significantly increased over the past 20-30 years, with teenage cases rising likely due to earlier puberty.
January 2020 in “Journal of clinical and cosmetic dermatology” This article reviews the etiology of FPHL, distinguishing between androgen-dependent and androgen-independent forms, but reports no new clinical findings; it highlights the need to better understand its pathogenesis.
January 2020 in “Advances in Sexual Medicine” This study suggests that female sexual dysfunction is not significantly associated with female pattern hair loss, but it may be more strongly influenced by age and parity in premenopausal women.
This study found that the patient receiving microneedling and platelet-rich plasma treatment showed earlier significant improvements and high satisfaction compared to the patient treated with microneedling and topical minoxidil.