3 citations
,
November 2023 in “Journal of Investigative Dermatology” Over 45% of patients with alopecia areata benefit from ritlecitinib, mostly within a year.
219 citations
,
March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
34 citations
,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.
21 citations
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August 1994 in “Clinical endocrinology” This article reviews the effects of 5 alpha-reductase inhibitors for treating conditions like male pattern baldness and benign prostatic hyperplasia, noting significant DHT reduction but reports no new clinical results.
20 citations
,
February 2002 in “Expert Opinion on Therapeutic Patents” This review discusses the potential uses of 5α-reductase inhibitors for conditions ranging from benign prostatic hyperplasia to skin disorders like acne and male pattern baldness, but it reports no new clinical results.
January 2022 in “Clinical Cases in Dermatology” This report describes a case of a 4-year-old boy diagnosed with linear alopecia areata, characterized by patchy hair loss and associated with unique hyperpigmented skin lesions.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
59 citations
,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that 4 weeks of finasteride treatment significantly decreased DHT levels in bald scalp to levels similar to hair-containing scalp in men with male pattern baldness.
6 citations
,
August 2013 in “한국응용생명화학회지” This study found that among eleven tested polymethoxyflavones, 5-hydroxy-7,4′-dimethoxyflavone was the strongest steroid 5α-reductase inhibitor and suggests potential use for benign prostatic hyperplasia treatment.
3 citations
,
January 2016 in “Skin appendage disorders” This case report describes a 45-year-old woman with diffuse nonscarring alopecia characterized by hair thinning, increased catagen/telogen follicles, and mild inflammatory infiltrate, highlighting the diagnostic findings via scalp dermoscopy and biopsy.
2 citations
,
June 2006 in “Experimental dermatology” This article discusses the development of skin patterns during embryogenesis and postnatal life, linking them to genetic, environmental, and mathematical factors, but presents no new empirical findings.
April 2024 in “Clinical dermatology review (Print)” In this descriptive hospital-based study, researchers found that telogen effluvium was the most common cause of hair loss among women aged 20 to 40, with most cases occurring over 6 weeks to 6 months without an associated illness.
January 2024 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that combining minoxidil 0.1% and dutasteride 0.01% applied topically after microneedling was significantly more effective than using dutasteride alone with microneedling in improving female pattern hair loss in 40 female patients.
This study found that 2-hydroxy-1,4-naphthoquinone was the most effective inhibitor of steroid 5α-reductase, showing stronger inhibition than avicequinone C in HaCaT cell assays.
February 2026 in “International Journal of Molecular Sciences” In this study, researchers identified 47 proteins associated with male pattern baldness severity and prioritized five candidate genes, including druggable CD38, suggesting new non-hormonal targets for therapeutic development.
28 citations
,
September 2014 in “Journal of Clinical Oncology” This study observed that frontal plus moderate vertex baldness at age 45 was associated with a higher risk of aggressive prostate cancer in a large cohort.
7 citations
,
January 2016 in “British Journal of Cancer” This study found that certain male pattern baldness subtypes at age 45 are associated with an increased risk of developing colorectal neoplasia.
275 citations
,
November 2002 in “International Journal of Dermatology” This study found that among an Asian population with alopecia areata, commonly first episodes occurred before age 40, with severe cases linked to psychological effects and treatments showing significant regrowth.
16 citations
,
July 1988 in “International Journal of Dermatology” This study found that 2% minoxidil solution significantly increased nonvellus hair count in men with male pattern baldness compared to placebo during a 48-week trial.
6 citations
,
August 2012 in “PubMed” In this report, a 44-year-old woman with female pattern alopecia experienced significant hair regrowth after 3.5 months of oral finasteride, with no side effects, after not responding to topical minoxidil.
1 citations
,
December 2022 in “BMC Plant Biology” This study suggests that the floral secretions of Brasiliorchis schunkeana may attract Diptera as potential pollinators, but field observations are needed to confirm this pollination syndrome.
May 2026 in “Journal of Drugs in Dermatology” This study reports that a dual cosmetic serum system by KilgourMD significantly improved hair loss in predominantly menopausal women over a 4-month period, as evidenced by objective and clinical assessments.
This study found that 23.2% of surveyed dermatologists in Saudi Arabia prescribe Tofacitinib for alopecia areata, with 72.4% reporting its effectiveness, while 47.7% cited unavailability as the main reason for not prescribing.
January 2023 in “International Journal of Molecular Sciences” This review discusses the biologically active compounds in Maxillariinae orchids, highlighting 62 semiochemicals with medical potential, but reports no new clinical findings.
January 2018 in “Figshare” There might be a link between male pattern baldness and a higher risk of prostate cancer and testicular cancer.
September 2019 in “Zagazig university medical journal” This study found that topical minoxidil 2% stimulated hair growth in women with female pattern hair loss after 4 months of treatment, though 55% reported side effects like dermatitis and hypertrichosis.
February 2023 in “Pakistan Journal of Medical and Health Sciences” This study found a variety of dermatological conditions in pregnant women, with Striae Gravidarum being the most prevalent at 48.1%, followed by Linea Nigra at 45.9%.
18 citations
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June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
16 citations
,
October 2003 in “Journal of The American Academy of Dermatology” This study describes a 4-year-old boy who exhibits a rare, synchronized pattern of hair growth and shedding, unlike the typical asynchronous pattern seen in humans.
January 2026 in “International Journal of Advanced Biochemistry Research” Among calves under one year in Uttarakhand, India, this study found that dermatophytosis prevalence was influenced by age, sex, breed, and season, with the highest rates in 4-6 month-olds, females, HF crossbreds, and during winter.