October 2024 in “Clinical and Experimental Dermatology” This study found that combining 17α-estradiol 0.01% with minoxidil 2% offered no statistically significant advantage over minoxidil alone for treating female pattern hair loss and may increase the risk of menstrual irregularities.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study demonstrated that both DKK2 and SOSTDC1 are necessary for normal timing of the first catagen phase in mice hair growth cycles.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the natural estrogen Estetrol (E4) may promote hair follicle growth and prevent miniaturization, suggesting its potential as a treatment for hair loss disorders.
October 2022 in “Hair Transplantation” This study reviewed preliminary evidence suggesting platelet-rich plasma could play a significant role in hair restoration, with animal experiments showing faster hair cycle transitions compared to controls.
September 2019 in “Journal of Investigative Dermatology” This study found that finasteride treatment reduced urinary androgen and prostaglandin levels in male pattern baldness patients to levels similar to healthy controls.
Using a specific laser and platelet-rich plasma together can effectively improve hair thickness and density in men with hair loss, without serious side effects.
April 2018 in “Journal of Investigative Dermatology” This study found distinct gene expression profiles in the parietal and occipital scalp of individuals with androgenetic alopecia, linked to developmental origins and susceptibility to hair loss, offering insights into genetic and epigenetic factors involved in AGA.
January 2014 in “프로그램북(구 초록집)” This review discusses various light and laser treatments for hair loss, highlighting potential benefits but emphasizes the need for more scientific evidence before recommendations can be made.
January 2008 in “Journal of The American Academy of Dermatology” ROS may affect hair loss related to hormones.
October 2021 in “Journal of Investigative Dermatology” This study found no significant epidemiological association between male androgenetic alopecia and severe Covid-19, but suggests a potential shared biological basis in specific pathways.
67 citations
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February 1994 in “Developmental dynamics” This study analyzed the distribution of adhesion molecules and extracellular matrix components in human fetal skin, suggesting their roles in hair follicle development.
July 2026 in “Journal of Investigative Dermatology” GLP-1 therapies can cause hair loss, but hair often regrows after stopping or reducing the drug.
176 citations
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May 2020 in “Dermatologic Therapy” This review discusses the cutaneous symptoms associated with COVID-19 and their potential use in diagnosing and assessing the severity of the disease, but it reports no new clinical results.
27 citations
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November 2020 in “International Journal of Dermatology” This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.
25 citations
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July 2021 in “Journal of Medical Virology” This review focuses on the various skin symptoms associated with COVID-19 but reports no new clinical findings.
9 citations
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January 2018 in “Indian Journal of Endocrinology and Metabolism” This study found that patients with androgenetic alopecia had a higher prevalence of metabolic syndrome compared to healthy controls.
April 2007 in “Nature Clinical Practice Urology” Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
123 citations
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May 2020 in “Drug Development Research” This article argues that androgen sensitivity could be a key factor in the severity of COVID-19, suggesting that trials with anti-androgen agents may be warranted.
71 citations
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April 2020 in “Journal of Cosmetic Dermatology” This article discusses the potential link between genetic variants associated with androgen receptor activity and racial variations in COVID-19 mortality, suggesting a possible role for anti-androgens in treatment, but reports no new clinical findings.
63 citations
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January 1999 in “The Journal of Clinical Endocrinology & Metabolism” This study found evidence suggesting a potential genetic link between polycystic ovaries and premature male pattern baldness through screening of first-degree relatives of women with polycystic ovary syndrome.
57 citations
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March 2011 in “The American Journal of Dermatopathology” This study found that permanent alopecia can occur after certain chemotherapy treatments and presents as nonscarring hair loss similar to androgenetic alopecia, with specific histological features that could be misdiagnosed without proper clinicopathological correlation.
56 citations
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January 2008 in “Dermatology” This article discusses the controversy over serum ferritin levels in diagnosing iron deficiency in women with hair loss but reports no new findings, emphasizing the need for consistent reference ranges.
41 citations
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January 2009 in “International Journal of Trichology” This study found that 58% of men aged 30-50 had androgenic alopecia, with disease severity increasing with age and many being candidates for medical treatment or hair transplantation.
36 citations
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November 2020 in “Journal of The European Academy of Dermatology and Venereology” This study found that 5-alpha-reductase inhibitors were associated with a reduced frequency of COVID-19 symptoms in males with androgenetic alopecia.
31 citations
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March 2017 in “Journal of The American Academy of Dermatology” This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.
30 citations
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April 2002 in “Archives of Dermatology” Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
27 citations
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December 2020 in “Experimental Dermatology” This study reported that COVID-19 was causally associated with postinfectious hair shedding, which varied with disease severity, but hair completely recovered.
24 citations
,
January 2010 in “Endocrine Regulations” In this study, men taking 1 mg/day of finasteride for 12 months showed minor metabolic changes and slight improvements in glucose metabolism.
21 citations
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November 2017 in “Scientific Reports” This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.
19 citations
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September 2009 in “The Journal of Dermatology” This article discusses the contributions of Dr. Shoji Okuda to the field of hair transplantation and reports no new research findings.