December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This paper identifies Galeal Tension-Induced Follicular Hypoxia as a mechanism for male pattern baldness, proposing a new therapeutic protocol targeting underlying physiological failures rather than just symptoms.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study elucidates a mechanism for male pattern baldness involving chronic scalp tension leading to follicular hypoxia, rather than purely hormonal factors, and proposes a treatment targeting electrolyte, vascular, and neurological factors to restore balance.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study elucidates a mechanism for male pattern baldness involving tension in scalp muscles that leads to reduced blood flow and hypoxia around hair follicles, proposing a multi-targeted therapeutic approach.
October 2025 in “Journal of the Endocrine Society” This case study reported that sudden hyperandrogenism in postmenopausal women may indicate hormonally active ovarian tumors such as Leydig cell tumors, which can be effectively treated with surgery.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study identified six molecules from herbal extracts that effectively bind to 5-alpha reductase (5-AR), with Jomogenin showing high binding stability when encapsulated in lipid nanoparticles, suggesting their potential for further experimental analysis to aid hair follicle growth.
June 2024 in “The Journal of Nutritional Biochemistry” This study found that 1,25-dihydroxyvitamin D3 promotes hair growth and regeneration in mice by prolonging the anagen phase and counteracting DHT's inhibitory effects, suggesting its potential therapeutic role for androgenetic alopecia.
April 2024 in “Clinical dermatology review (Print)” In this descriptive hospital-based study, researchers found that telogen effluvium was the most common cause of hair loss among women aged 20 to 40, with most cases occurring over 6 weeks to 6 months without an associated illness.
April 2023 in “Voprosy kurortologii fizioterapii i lechebnoĭ fizicheskoĭ kultury” This study reported that 19.8% of patients experienced telogen hair loss after COVID-19, with most cases occurring 3 to 6 months post-recovery, and noted a rapid progression in patients with androgenetic alopecia, as well as cases of alopecia areata and cicatricial alopecia linked to COVID-19.
This study found a significant correlation between age and androgen alopecia levels in male patients with COVID-19, and it suggests an association between gender and androgen alopecia prevalence in this hospitalized group.
January 2023 in “Advances in reproductive sciences” This study found that women with PCOS and female androgenetic alopecia had significantly higher serum pannexin-1 channel levels compared to those without PCOS, suggesting a potential role in hair loss etiology.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.
January 2021 in “Annals of Chinese medicine” This article compares Chinese medicine theories with male androgenetic alopecia progression and reports no new clinical results, noting an overlap in MAA pathogenesis with some COVID-19 conditions and proposing acupuncture points for treatment.
September 2020 in “Annals of the National Academy of Medical Sciences. India” This article discusses the impact of COVID-19 on skin health, highlighting various cutaneous manifestations and the need for dermatologists to adapt their practices during the pandemic, but it reports no new results.
April 2020 in “Journal of the Endocrine Society” This case report describes a 58-year-old woman whose virilization symptoms were linked to a steroid tumor of the ovary, emphasizing the importance of prompt diagnosis and treatment to improve her quality of life.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that in an ex vivo setting, 17β-estradiol increased CB1 expression in human hair follicles, suggesting possible sensitivity to endocannabinoids and a potential mechanism for hair therapy.
April 2018 in “Journal of Investigative Dermatology” This study found that a water-soluble peptide from chicken egg yolk, named Hair Growth Peptide, improved hair growth in mice and female pattern hair loss through increased IGF-1 and VEGF production.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
January 2014 in “eScholarship (California Digital Library)” In this study, researchers observed that TLR3 and scavenger receptors play key roles in skin barrier repair following UVB damage, contributing to our understanding of cellular responses to skin injury.
March 2012 in “Journal of The American Academy of Dermatology” Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.
June 2006 in “Experimental Dermatology” This article discusses various biological mechanisms that influence the formation of skin lesion patterns, emphasizing the need for more systematic research to improve understanding and treatment of skin disorders, but reports no new empirical findings.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
October 2021 in “QJM: An International Journal of Medicine” This study found that injection of adipose-derived adult stem cells improved hair density, thickness, and reduced inflammation in women with female pattern hair loss over 24 weeks.
October 2020 in “Clinical and Experimental Dermatology” Hair loss improved after removing pituitary tumor.
August 2020 in “International Journal of Medical Arts (Print)” This study found that topical cetirizine 1% may be effective in treating androgenetic alopecia in men, with some patients experiencing new hair growth compared to none in the placebo group.
August 2019 in “Journal of Dermatology” This article is a letter to the editor discussing a rare case of Leydig cell tumor with type I diabetes mellitus causing female pattern hair loss, but it contains no abstract or new clinical findings.
December 2018 in “Evidence-Based Practice” Topical minoxidil 1% and 2% are twice as effective as placebo for female pattern hair loss.
January 2014 in “프로그램북(구 초록집)” This article reviews updates on 5 alpha-reductase inhibitors for treating male pattern hair loss and presents no new clinical findings; the author aims to enhance understanding of these therapies.
December 2022 in “Pakistan Armed Forces Medical Journal” This study suggests that a high frequency of androgenetic alopecia is associated with increased severity of COVID-19 in hospitalized patients.
This study compares datasets to analyze the prevalence of androgenetic alopecia in patients admitted with severe COVID-19 in three Madrid hospitals, focusing on age, gender, and alopecia severity.
April 2018 in “Journal of Investigative Dermatology” This study used single-cell RNA sequencing to identify at least nine subpopulations of keratinocytes in human neonatal epidermis, revealing unexpected heterogeneity and complex differentiation trajectories.