38 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review summarizes existing research on the use of finasteride for treating androgenetic alopecia in men, reporting its effectiveness at 1 mg/day and a strong safety profile, but presents no new findings.
33 citations
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November 2012 in “Journal of The American Academy of Dermatology” This study reported that female pattern hair loss was prevalent in 11.8% of women aged 30 and older and was associated with high fasting glucose, fewer childbirths, oral contraceptive use, and excessive ultraviolet exposure.
26 citations
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May 2017 in “Lasers in Medical Science” This study found that combining ablative fractional CO₂ laser therapy with hair growth factors significantly increased hair density in men with androgenetic alopecia compared to using growth factors alone.
24 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study found that 1% and 2% topical minoxidil solutions resulted in clinically noticeable hair growth compared to lower doses or placebo in men with male pattern baldness.
12 citations
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October 2004 in “PubMed” This study found that finasteride 1 mg per day improved hair growth and slowed hair loss in Japanese men with male pattern hair loss compared to lower doses and placebo.
8 citations
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April 2017 in “Experimental Dermatology” This study found that men with androgenetic alopecia had significantly higher plasma leptin levels, which were associated with an increased risk of developing the condition.
7 citations
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September 2004 in “대한의생명과학회지” This study suggests that a topical oriental medicine extract may improve hair density and scalp condition in individuals experiencing male pattern hair loss after 18 months of use.
6 citations
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December 2022 in “Biomedicines” This study found that the expression of the sonic hedgehog protein is involved in wound healing texture regeneration, inhibiting skin texture after embryonic day 14 and affecting keratinocyte migration and division.
6 citations
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January 2003 in “Dermatology” This study reviewed 26 cases of X-linked recessive ichthyosis and observed 11 patients with advanced-stage androgenetic alopecia, suggesting a compensatory role of two steroid biosynthesis pathways.
4 citations
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February 2018 in “Journal of Investigative Dermatology” This study suggests that thermal imaging may aid in diagnosing cellulitis, potentially improving patient care, although its applicability to certain cases requires further investigation.
4 citations
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March 2017 in “PubMed” This study found that a 15% topical minoxidil solution improved hair regrowth in 60% of women with female pattern hair loss who did not respond to the standard 5% solution, without adverse effects.
2 citations
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October 2021 in “Exploration of targeted anti-tumor therapy” This review describes oncotherapy-induced alopecia in patients receiving hormone therapy for hormone-receptor-positive breast cancer and concludes that topical hormones should not be used due to oncogenic potential.
2 citations
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April 2016 in “PubMed” This study found that a 12-week regimen of 2% minoxidil combined with a botanical hair solution improved hair growth and patient satisfaction for female pattern hair loss, aiding treatment adherence.
1 citations
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December 2022 in “BMC Plant Biology” This study suggests that the floral secretions of Brasiliorchis schunkeana may attract Diptera as potential pollinators, but field observations are needed to confirm this pollination syndrome.
1 citations
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September 2021 in “Skin appendage disorders” This systematic review of five studies found that intradermal and intramuscular botulinum toxin injections showed promising hair growth outcomes for men with androgenic alopecia, but emphasizes caution due to a lack of control groups and small sample sizes.
1 citations
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October 2019 in “مجله كليه طب الكندي” In this study, researchers highlight the role of androgens like dihydrotestosterone in the pathophysiology of acne, pointing to the enzyme 5a-reductase type 1 as potentially more active in individuals with acne, which may contribute to hormonal influences in the condition's development.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study found that a novel 15% topical minoxidil solution achieved a clinically significant hair regrowth response in 60% of women with female pattern hair loss who did not respond to 5% minoxidil, without increasing adverse events.
August 2026 in “Dermatology and Therapy” This retrospective cohort study found that both spironolactone and bicalutamide significantly improved Sinclair grade in women with female pattern hair loss over 24 months, but spironolactone, especially at doses above 100 mg/day, resulted in greater efficacy, required less monitoring, and maintained comparable safety.
July 2026 in “European Journal of Plastic Surgery” This study found that combining needle-free intradermal minoxidil delivery with standard topical minoxidil therapy improved early hair growth parameters and satisfaction in women with early-stage female pattern hair loss compared to topical therapy alone, with no serious adverse events reported over the 10-week period.
September 2025 in “International Journal of Women’s Dermatology” This study found that oral spironolactone 100 mg daily for 24 weeks improved terminal hair counts and diameters in premenopausal women with female pattern hair loss when used alongside minoxidil, despite a higher incidence of menstrual irregularities.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.
January 2025 in “International Journal of Medical Arts” This study found that a topical 1.0% sildenafil citrate solution significantly increased vellus and terminal hairs in women with female pattern hair loss without affecting hair thickness, suggesting it may be a promising treatment option.
December 2024 in “International Journal of Drug Delivery Technology” In this study, researchers developed and evaluated a topical dutasteride gel for treating male pattern baldness, finding that a formulation with 10% garlic extract showed the most promising results in promoting faster hair growth compared to other formulations tested.
October 2024 in “Journal of Drugs in Dermatology” This study found that a combination of topical finasteride 0.25% with minoxidil 5% was more effective than using topical minoxidil 5% alone for treating male pattern androgenic alopecia over a 12-week period.
September 2024 in “Journal of the American Academy of Dermatology” This meta-analysis found that smoking is significantly associated with increased odds of developing and progressing androgenetic alopecia, with higher risks observed in men smoking at least 10 cigarettes daily.
August 2024 in “Skin Research and Technology” This case study involving a 63-year-old woman with female pattern hair loss found that a 3-month regimen of low-dose oral minoxidil increased hair density from 98 to 140 hairs per square centimeter, but caution was advised regarding its safety and efficacy without larger trials.
June 2024 in “Archives of dermatological research” In this self-controlled comparative study of 16 women with Female Pattern Hair Loss, MMP® with Minoxidil showed a better response in the parietal-vertex regions in less advanced cases compared to standard Minoxidil treatment, though overall effectiveness was similar.
In this study, 13 men with male pattern baldness were rated significantly more attractive and somewhat healthier when wearing a custom-made toupee, with higher attractiveness ratings coming from male judges than female judges.
November 2023 in “Journal of Cosmetic Dermatology” This study found that a 12-week topical treatment with a caffeine and Procapil 3% formulation effectively reduced hair loss by 26.9% and improved hair growth in men with androgenetic alopecia, without any reported adverse effects.
August 2021 in “Clinical and Experimental Dermatology” This article discusses the introduction of the term 'prepubertal pattern hair loss' to describe hair thinning in children under 10 without physical abnormalities, and reports no new clinical findings.