March 2021 in “Der Hautarzt” This review covers the clinical features, pathophysiology, differential diagnoses, and therapeutic options for neuroendocrine paraneoplastic syndromes affecting the skin but reports no new clinical findings.
November 2020 in “Journal of The American Academy of Dermatology” This article comments on previous studies linking severe androgenetic alopecia to increased vulnerability to COVID-19 and highlights ongoing research into antiandrogen therapies as potential treatments.
January 2018 in “Genetic engineering & biotechnology news” A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.
March 2017 in “International Society of Hair Restoration Surgery” Female hair loss may be linked to heart health and aging.
March 2012 in “Journal of The American Academy of Dermatology” Hair casts are often mistaken for head lice, scalp pain in hair loss is linked to certain nerve factors, eyelash growth treatment is safe and effective, and nail shedding in children may follow hand-foot-mouth disease.
December 2010 in “Vestnik dermatologii i venerologii” This article reviews molecular and genetic mechanisms in the development of androgenic alopecia and examines the relationship between androgen receptor gene polymorphism and androgen-dependent diseases, but reports no new clinical results.
July 2010 in “Journal of Investigative Dermatology” Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.
October 2007 in “Journal of Investigative Dermatology” The meeting highlighted the genetic basis of female pattern hair loss and various skin health insights.
January 2007 in “Inpharma Weekly” Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the latest findings presented at the 4th Intercontinental Meeting of Hair Research Societies, covering advances in hair follicle biology, genetic bases for hair disorders, and potential new therapeutic approaches, but it reports no original study results.
This study aims to develop an automatic machine learning-based method using the VGG-19 model to accurately classify various hair and scalp diseases.
March 2023 in “Research Square (Research Square)” In this study, researchers found that changes in immune cell infiltration and immune-related gene expression may contribute to the immune microenvironment changes in male androgenetic alopecia.
March 2023 in “Civil Medical Journal” This observational study found that 37% of male patients with androgenetic alopecia had a history of preceding COVID-19 infection, suggesting a potential link between the two.
January 2022 in “Biomedical Reports” This study suggests that inaudible sound at 30 kHz may promote hair growth and inhibit hair loss signals in human dermal papilla cells, indicating potential as a new treatment for androgenic alopecia.
January 1999 in “Journal of S C C J” This study found that STAT3 signaling is essential for initiating the hair growth phase but not involved in hair follicle development during the fetal period.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” New treatment improves male hair loss.
January 2024 in “Journal of Cosmetics Dermatological Sciences and Applications” This study found that 23.8% of participants with pattern hair loss had occipital involvement, with higher rates in females (35.6%) compared to males with early-stage hair loss (12.1%), illustrating significant gender differences in hair loss progression.
18 citations
,
June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
July 2025 in “Journal of Cosmetic Dermatology” This study analyzed global research on female pattern hair loss from 1957 to 2024, reporting trends in publication output and hotspots in topics like treatment mechanisms and safety, with the USA leading in contributions and citations.
44 citations
,
March 2004 in “Journal of Investigative Dermatology” This study observed that in vitro treatment of male frontotemporal scalp hair follicles with 17-β-estradiol stimulated hair shaft generation and hair matrix keratinocyte proliferation, suggesting potential anagen-prolonging effects.
34 citations
,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.
29 citations
,
February 2004 in “Experimental and Clinical Endocrinology & Diabetes” This study suggests that many men with premature balding exhibit a hormonal pattern similar to some aspects of polycystic ovary syndrome in women.
29 citations
,
May 1986 in “Journal of Steroid Biochemistry” Androgens don't directly affect hair cell growth or protein production.
27 citations
,
July 1982 in “British Journal of Dermatology” The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
23 citations
,
June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
21 citations
,
January 2003 in “Skin pharmacology and physiology” This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.
20 citations
,
February 2002 in “Expert Opinion on Therapeutic Patents” This review discusses the potential uses of 5α-reductase inhibitors for conditions ranging from benign prostatic hyperplasia to skin disorders like acne and male pattern baldness, but it reports no new clinical results.
13 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This study observed that human anagen hair follicles can grow in vitro when maintained serum-free, with possible implications for understanding hair follicle growth mechanisms.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” This summary reviews the conflicting reports regarding 17β‐estradiol's effects on hair follicle growth, highlighting potential estrogen receptor-mediated impacts and calling for further research.
In this observational study, dutasteride treatment was associated with statistically significant stabilization of frontal fibrosing alopecia compared to other systemic therapies, with a dose-dependent effect observed across the frontal and bilateral temporal hairlines.