This chapter reviews the pathophysiology of immune checkpoint inhibitor-related endocrinopathies and examines the rationale for using advanced diabetes care technologies, like pump therapies and continuous glucose monitors, in managing these conditions.
July 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the pathophysiology of alopecia areata, highlighting the role of CD8 cytotoxic T cells and the upregulation of JAK signaling pathways; it reports no new experimental results.
May 2023 in “Journal of managed care & specialty pharmacy” This review discusses the pathophysiology, economic burden, and treatment options of alopecia areata and reports no new clinical results, highlighting the need for better therapies, including JAK inhibitors.
August 2019 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This review discusses the pathophysiology of polycystic ovary syndrome and its non-pharmacological and pharmacological treatment options, but reports no new clinical results.
April 2017 in “Journal of Investigative Dermatology” This study found that sulfated CCK octapeptide reduces psoriasis-like skin inflammation in mice, suggesting a new pathophysiological role for CCK in regulating epidermal inflammation.
February 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the pathophysiology of psoriasis and available treatment options but reports no clinical trial results.
January 2013 in “Российский журнал кожных и венерических болезней” This article reviews the pathophysiology and limited effectiveness of current treatments for androgenic alopecia, including finasteride, minoxidil, botulinum toxin A, and platelet-rich plasma, and highlights the need for new therapeutic approaches; it reports no new clinical findings.
December 2022 in “International Journal of Health Science” This review discusses the pathophysiological impacts of hyperandrogenism in women with PCOS and reports no new clinical results; the authors highlight lifestyle changes as a primary management strategy.
August 2019 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This review discusses the pathophysiological characteristics and treatment options for polycystic ovary syndrome, reporting no new clinical results; the authors emphasize combining non-pharmacological measures with pharmacological treatments for optimal patient management.
January 2005 in “Life sciences” This review discusses the pathophysiologic role of lysophosphatidic acid in the skin and reports no clinical results, suggesting pharmacological inhibition as a potential treatment for various skin disorders.
69 citations
,
November 2010 in “Middle East Fertility Society Journal” This review discusses the multifactorial origins and pathophysiology of PCOS and highlights the effectiveness of lifestyle modifications as a first-line intervention, reporting no new research results.
21 citations
,
January 2003 in “Seminars in reproductive medicine” This review outlines the underlying pathophysiology and treatment options for the androgen excess and reproductive and metabolic manifestations of polycystic ovary syndrome, but reports no clinical results.
7 citations
,
January 2013 in “International Journal of Oral and Maxillofacial Surgery” This review discusses the anatomy, aging pathophysiology, and various surgical and non-surgical options for rejuvenating the upper face, including antioxidants and non-ablation laser, but reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the complex pathophysiology of androgenetic alopecia, highlighting genetic factors, androgen metabolism, and emerging therapies such as platelet-rich plasma and low-level laser therapy, but notes that no ultimate cure exists and treatments focus on slowing progression and promoting hair growth.
June 2023 in “Lithuanian University of Health Sciences” This review found that the pathophysiology of polycystic ovary syndrome is associated with increased rates of gestational diabetes, pregnancy-induced hypertension, caesarian deliveries, and adverse effects on preterm birth and neonatal weight during pregnancy.
December 2022 in “BioScientific review” This review discusses the complex pathophysiology, diagnosis, and management of Polycystic Ovary Syndrome and reports no new results, underscoring the need for comprehensive treatment plans.
May 1962 in “Zhurnal Fizicheskoi Khimii (U.S.S.R.) For English translation see Russ. J. Phys. Chem. (Engl. Transl.)” This review discusses the complex pathophysiology of polycystic ovary syndrome and reports no clinical trial results, emphasizing the need for better understanding to improve treatment options.
13 citations
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January 2016 in “Journal of cosmetology & trichology” This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
78 citations
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June 2021 in “Dermatology and Therapy” This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.
1 citations
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March 2021 in “Dermatological reviews” This review discusses recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia in males, females, and children, but reports no new clinical results.
1 citations
,
February 2017 in “MOJ bioequivalence & bioavailability” This review discusses recent advancements in understanding the pathophysiology of androgenetic alopecia and highlights the potential for multilateral topical therapies to improve treatment efficacy with fewer side effects; it reports no new clinical results.
May 2026 in “Frontiers in Immunology” This review discusses the dual role of extracellular vesicles in the pathophysiology and treatment of atopic dermatitis but reports no new clinical results; future research should address standardization and safety challenges.
This review discusses the unique characteristics and possible pathophysiology of spiny keratoderma, reporting no new clinical results, but suggests that some therapies might alleviate symptoms.
June 2018 in “The Journal of Sexual Medicine” This study used high-resolution ultrasound to investigate the pathophysiology of persistent erectile dysfunction in young men who used the drug finasteride, observing differences in erectile tissue homogeneity compared to control subjects without finasteride exposure.
3 citations
,
April 2020 in “Journal of Mind and Medical Sciences” This review discusses the reproductive challenges and potential pathophysiological mechanisms related to anorexia nervosa, noting possible long-term effects on fertility and pregnancy outcomes.
117 citations
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May 2017 in “Human Reproduction Update” This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.
36 citations
,
January 2023 in “Skin Appendage Disorders” This review discusses the etiology, pathophysiology, trichoscopic characteristics, differential diagnoses, and treatment options for scalp seborrheic dermatitis, without providing new clinical findings.
35 citations
,
October 2019 in “Journal of pediatric health care” This article reviews the clinical presentations, pathophysiology, and treatment options for various skin conditions in children with skin of color and reports no new findings.
28 citations
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November 2007 in “Medical Clinics of North America” This review discusses the impact, pathophysiology, and health risks of obesity and the metabolic syndrome in polycystic ovarian syndrome, emphasizing the potential life-saving benefits of recognition and treatment, but it reports no new results.