research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
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research Calreticulin: Non-Endoplasmic Reticulum Functions in Physiology and Disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Cutaneous Syndromes Produced as Side Effects of Triparanol Therapy
Triparanol therapy can cause hair loss and skin dryness without inflammation or damage to hair follicles or skin structures.
research Generalized Hair Follicle Hamartoma Associated With Alopecia And Myasthenia Gravis: Report Of A Second Case
A possible link exists between hair follicle abnormalities, hair loss, and muscle weakness.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics
Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
research The Skin in Pregnancy: A Review of Normal Changes
Pregnancy can cause normal skin changes that usually go away after childbirth and don't need treatment.
research The Diagnosis and Treatment of Hair and Scalp Diseases
Hair loss requires customized treatments based on its various causes and types.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
research Expanding Clinical Indications of Mechanically Isolated Stromal Vascular Fraction: A Systematic Review
The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.
research Loose Anagen Hair
Loose anagen hair can appear at any age and may improve over time.
research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs as New Molecular Players in Dermatology and Cutaneous Biology
Non-coding RNAs are crucial for skin development and health.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Alopecia Mucinosa
Alopecia mucinosa causes red, raised skin patches and hair loss.
research A Clinical Study of Geriatric Dermatoses
Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
research Vitamin D Receptor Ablation Alters Skin Architecture and Homeostasis of Dendritic Epidermal T Cells
Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.
research Clinical Presentation and Management Outcome of Childhood-Onset Systemic Lupus Erythematosus in Baghdad
Most children with childhood-onset lupus in Baghdad responded well to treatment, but some developed chronic kidney disease or died.
research The Treatment of Acne
Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.
research Wild Geladas (Theropithecus Gelada) in Crops Reduce Aggression and Affiliation More Than in Pasture Areas
Wild geladas in crop areas show less grooming and aggression.
research Heme Oxygenase and the Skin in Health and Disease
HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
research Hair Tourniquet Syndrome of Penis: A Rare Situation in Boys with Serious Complications if Not Recognized
Hair wrapped tightly around a boy's penis can cause serious damage if not treated quickly.
research Plaque-Type Herpetic Folliculitis Involving the Eccrine Gland: Immunohistochemical Analysis
Plaque-type herpetic folliculitis affects eccrine glands.
research Targeting Cardiac Hypertrophy Through a Nuclear Co-Repressor
Targeting NCoR1 can help treat heart enlargement and dysfunction.
research Vulvar Fordyce Adenitis: A Cohort of 45 Women
Vulvar acne, also known as "vulvar Fordyce adenitis", is a condition causing painful bumps on the labia, and it's not always effectively treated with common acne medications, but isotretinoin has shown promise.
research Dermatology and Pregnancy
Pregnancy can cause skin changes and affect existing skin conditions, with limited treatment options due to the need for fetal safety.
research Nails and Hair
Hair and nails can help diagnose diseases, with nail issues often linked to skin conditions and hair loss having various causes and treatments.
research Brazilian Pulmonology Guidelines on Delphi Panel for Post-Coronavirus Disease 2019
Experts agree on the need for standardized definitions and education for post-COVID-19 conditions.