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Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Combination therapy works best for female hair loss, increasing density and thickness.

PRP treatment improves hair count, density, and reduces hair loss in AGA patients.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.