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This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.

This study found that cotreatment with graphene oxide and indole-3-acetic acid significantly inhibited root development in Brassica napus, with the inhibition increasing as indole-3-acetic acid concentration rose.

This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.

This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.

This study observed high expression of mTOR pathway effectors in fibrous papules and TSC-associated angiofibromas, suggesting that topical rapamycin might be an effective treatment for fibrous papules.

This review discusses the potential of JAK inhibitors as a promising treatment strategy for alopecia areata, highlighting their mechanism and recent FDA approval based on clinical trial efficacy.

This study found that combining platelet-rich plasma with adipose-derived mesenchymal stem cells significantly improved diabetic wound healing in rats by enhancing angiogenesis and modulating the Notch signaling pathway.

This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.

This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.

This study observed that proteins in the mTOR signaling pathway are expressed differently in the hair follicles of patients with lichen planopilaris and frontal fibrosing alopecia, suggesting a role in the pathogenesis of these conditions.

In this study, researchers observed that Zibai ointment promoted chronic wound healing in rats by influencing the bFGF/Wnt/β-Catenin signaling pathway, demonstrating a higher wound healing rate compared to other treatments.

This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.

This review found that JAK/STAT pathway inhibitors, such as tofacitinib and ruxolitinib, led to symptom improvement in all observed atopic dermatitis cases, but responses were mixed for vitiligo and alopecia areata, with a generally mild safety profile reported.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

This study reports that Lef1 plays a crucial role in promoting bulge stem cell differentiation towards hair fate by activating β-catenin and downstream signaling pathways during hair follicle development.

In this study, the researchers reported that activin B combined with bone marrow-derived mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats by promoting cell migration through the ERK and JNK pathways.

This study investigated the role of NLRP3 inflammasomes in alopecia areata and found that outer root sheath cells may contribute to inflammation by increasing IL-1β and HMGB1 secretion when stimulated with double-stranded RNA.

In this study, researchers overexpressed Lrig3 in mouse skin and observed hair loss linked to changes in skin protein profiles and signaling pathways, suggesting a potential role for Lrig3 in maintaining skin homeostasis.

This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.

In this retrospective study, researchers found that baricitinib was effective for treating moderate to severe alopecia areata, with response rates in 24 patients comparable to existing real-world data, and no new safety concerns were identified.

This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.

This study suggests that in SZ95 sebocytes, a pathway for DHT biosynthesis does not require testosterone as an intermediate, potentially impacting the treatment of androgen-sensitive skin conditions.

This study found that pharmacological inhibition of sex steroid synthesis impacts pathogenic processes in traumatic brain injury in a sex-specific manner, with distinct effects of letrozole and finasteride on molecular and neurological outcomes.

This study found that AA may have a protective role in the progression of both HBDC and CRC, suggesting potential new research avenues for treatments of these conditions.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

Understanding how our bodies interact with mosquito-borne viruses is crucial because there are few treatments and vaccines.

This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.