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MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Chicken feather gene mutation helps understand human hair disorders.

Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.

Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

Understanding skin structure and development helps diagnose and treat skin disorders.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

The skin and thymus develop similarly to protect and support immunity.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Hair loss in Cronkhite-Canada syndrome may be due to an autoimmune response.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Enzymes called PADIs play a key role in hair growth and loss.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.