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Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Garden cress extract may help treat skin inflammation and androgen-related disorders.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Lower vitamin D levels may contribute to female hair loss.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

New treatments for PCOS focus on managing symptoms and improving fertility.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

ADAM17 could be a potential target for treating PCOS.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.