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The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

TLR2 is important for hair growth and can be targeted to treat hair loss.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Skin fat helps with body temperature control and has other active roles in health.

Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.

Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.