September 2009 in “Journal of the Dermatology Nurses’ Association” Hair loss significantly affects quality of life, wet combing is better than visual inspection for finding head lice, many with oral lichen planus have allergies, and wet wraps with steroids quickly improve itchy skin conditions.
2 citations
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January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
February 2024 in “The Open dermatology journal” This systematic review reported that alopecia areata significantly impacts quality of life due to its psychological burdens, such as anxiety and depression, while emphasizing the need for increased awareness and support for affected individuals.
July 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the pathophysiology of alopecia areata, highlighting the role of CD8 cytotoxic T cells and the upregulation of JAK signaling pathways; it reports no new experimental results.
8 citations
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June 2022 in “Frontiers in bioengineering and biotechnology” This study found that a collagen patch made with fibroblast-derived extracellular matrix (fdECM) extracted from human lung fibroblasts enhanced wound healing by promoting wound contraction, angiogenesis, and skin remodeling in full-thickness skin wound models, including those with diabetic ulcers.
1 citations
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August 2023 in “Advanced Drug Delivery Reviews” This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.
November 2013 in “Annales de Dermatologie et de Vénéréologie” This study found that extracts of Punica granatum L. improved hair growth and demonstrated significant anti-lice and antidandruff activity in a mouse model.
36 citations
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June 2018 in “Journal of The American Academy of Dermatology” This review examines the increasing clinical applications of dermoscopy in diagnosing various skin conditions and highlights its potential to improve diagnostic accuracy and reduce unnecessary histologic confirmation.
February 2026 in “Journal of the American Academy of Dermatology” In this study, researchers characterized the clinical features of ophiasis, an uncommon type of alopecia areata, and proposed a new subtype classification that may help predict treatment response and guide management, noting that ophiasis generally has a chronic and refractory nature.
16 citations
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May 2022 in “New England Journal of Medicine” This Italian study observed that one third of patients with 25 to 50% scalp hair loss from alopecia areata still experienced active patchy disease at long-term follow-up, and another third progressed to more severe forms like alopecia totalis or universalis, with limited recovery.
January 2023 in “Social Science Research Network” This case study describes the treatment of a 27-year-old Filipino male with acute patchy hair loss due to alopecia areata, emphasizing the disease's unpredictable progression.
February 2010 in “Journal of The American Academy of Dermatology” This study found that among Chinese patients with alopecia areata, those with alopecia totalis or universalis had an earlier onset, longer disease duration, and more severe quality of life impact than those with patchy alopecia.
35 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.
June 2026 in “JAAD Case Reports” This case report details a 77-year-old man with Parkinson's disease and androgenic alopecia who underwent deep brain stimulation surgery, involving frontal scalp incisions and subcutaneous wire tunneling.
3 citations
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April 2023 in “Dermatologica Sinica” This study found that platelet-rich plasma treatment was an effective and safe option for reducing severity in patients with mild patch-type alopecia areata.
1 citations
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October 2006 in “Journal of Family Planning and Reproductive Health Care” This case report describes a woman who developed a 5 cm patch of scalp hair loss four months after receiving an Implanon contraceptive implant, with no previous history of hair loss or scalp issues.
March 2026 in “Minia Journal of Medical Research” In this prospective study, patients with patchy alopecia areata showed significant dermoscopic improvement after three months of topical corticosteroid treatment, with a marked decrease in activity signs and increase in regrowth features.
November 2025 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” This study found that intralesional vitamin D3 injections significantly increased serum vitamin D3 levels in patients with localized alopecia areata, although baseline vitamin D3 levels did not predict disease severity or treatment response.
5 citations
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August 1925 in “Archives of dermatology” This article presents a case of an 8-year-old boy with Recklinghausen's disease showing features such as café-au-lait spots, alopecia, and developmental anomalies, but reports no new findings beyond observation.
June 2026 in “Research Square” This study found that lower vitamin D levels were inversely associated with the severity of female pattern hair loss and patchy alopecia areata, but not with telogen effluvium.
This study highlights the use of dermatoscopy as a valuable tool for diagnosing and monitoring alopecia areata, noting that specific hair shaft alterations such as exclamation-mark hairs and black dots are indicators of active disease, while vellus hairs signal early regrowth.
July 2024 in “Journal of Pakistan Association of Dermatologists” In this study of alopecia areata patients, researchers reported that nail changes are significantly associated with severe disease, and dermoscopic analysis revealed a notable correlation between yellow dots and increased disease severity, with the condition primarily affecting young adults and more common in males.
1 citations
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October 2015 in “Joint bone spine” This study found that ankylosing spondylitis patients who are members of a self-help organization tend to have higher educational levels, are better informed about their disease, and have better functional outcomes than non-members, although potential confounders may affect disease outcome measures.
January 2024 in “Dermatology practical & conceptual” In this study, researchers evaluated factors influencing alopecia areata recurrence and identified male gender and a family history of the condition as independent predictors for disease recurrence among the 100 patients analyzed.
44 citations
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December 2005 in “Journal of Investigative Dermatology” This study found significant associations between certain MICA variants and haplotypes with alopecia areata, suggesting MICA as a potential candidate gene linked to the disease's susceptibility and severity.
36 citations
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May 2011 in “Dermatologic therapy” This review discusses topical and intralesional treatments for alopecia areata, providing a management strategy based on patient age and disease severity, but reports no new clinical results.
16 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that intramuscular anti-IFN-γ significantly stabilized and promoted hair regrowth in alopecia areata patients with patchy, progressive hair loss, whereas those with total baldness showed more limited improvement.
7 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.
May 2024 in “Journal of cosmetic dermatology” In this retrospective study, oral tofacitinib treatment for at least 6 months improved scalp hair loss in 69.1% of alopecia areata patients, with patchy AA cases responding better compared to other subtypes, and no significant adverse effects were reported.
4 citations
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March 2025 in “Pediatric Dermatology” This review examines the clinical presentation of alopecia areata in children and compares it to adult-onset cases, noting that data on pediatric cases is scarce and often varies, with reported onset typically between ages 6 and 12.