2 citations
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October 1990 in “PubMed” This study suggests that autoimmune dysregulation involving HLA-DR+ T and NK cell subsets may contribute to severe patchy alopecia areata and alopecia universalis, with normalization seen after betamethasone treatment.
1 citations
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October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that low serum ferritin levels in pediatric patients with alopecia areata were associated with increased disease severity and longer duration.
November 2024 in “Journal of Investigative Dermatology” This study found that scarring alopecia is common in autosomal recessive congenital ichthyosis patients and significantly correlates with the disease's severity, highlighting the need for thorough hair evaluations in clinical management.
February 2010 in “Journal of The American Academy of Dermatology” This study found that Chinese patients with alopecia totalis or universalis had an earlier onset, longer disease duration, and more severe quality of life impact compared to those with patchy alopecia areata.
5 citations
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January 2018 in “PubMed” In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.
11 citations
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January 2013 in “International Journal of Trichology” This article reports a case of neurodermatitis where a combination of intralesional steroids, oral doxepin, and psychotherapy resulted in complete symptom remission and hair regrowth, highlighting the importance of addressing emotional factors in treatment.
9 citations
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July 2020 in “JAMA dermatology” This study explored dermatoscopic and histopathologic findings of central centrifugal cicatricial alopecia beyond the vertex scalp, suggesting that dermatoscopy might serve as a less invasive diagnostic tool for subclinical disease.
5 citations
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October 1984 in “The BMJ” Up to 50% of scalp hair can be lost before it appears thin, and treatment is only needed for hair loss caused by diseases or deficiencies.
3 citations
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December 2018 in “Journal of Pakistan Association of Dermatology” This study found that patients with alopecia areata often presented with multilocular patches, common scalp involvement, and associated conditions like atopic dermatitis; the disease predominantly affected younger individuals.
2 citations
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August 2020 in “Journal of Cosmetic Dermatology” This study found that in patients with alopecia areata, serum granulysin levels decreased significantly after treatment with tofacitinib and correlated with reduced disease severity, suggesting serum granulysin as an indicator of immunological activity and response to therapy.
1 citations
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October 2020 in “International Journal of Research in Dermatology” This study found that short vellus hair and yellow dots are common dermoscopic findings in alopecia areata, with variations indicating disease activity or remission.
This review explores the Ayurvedic perspective of Indralupta, linked to Alopecia areata in modern medicine, highlighting disease progression through Tridosha imbalance and comparing it with contemporary understanding of Alopecia's pathogenesis.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review correlates Indralupta, described in Ayurveda, with modern Alopecia Areata, elaborating on its disease progression and pathogenesis involving Tridosha imbalance, primarily Pitta and Vata, and Rakta dushti, for a better understanding of intervention approaches.
December 2025 in “Cureus” In this case report, a unique immunological mechanism was observed in an 11-year-old girl where the presence of one autoimmune disease appeared to prevent the manifestation of another, leading to the withdrawal of one type of lesion when another appeared.
May 2024 in “Journal of Pakistan Association of Dermatologists” This study observed no statistically significant relationship between vitamin D levels and alopecia areata, including different types of the disease, suggesting vitamin D may not play a central role in its development or extent among a sample of adults.
January 2023 in “Asian Journal of Pediatric Research” This study identified black dots as the most common trichoscopic sign in children with alopecia areata, which is crucial for diagnosis and understanding disease severity and prognosis.
January 2015 in “Springer eBooks” Hair damage shows as fragility, dullness, and discoloration, varies by ethnicity, and is worsened by cosmetic procedures and diseases.
December 1977 in “Archives of Dermatology” This letter discusses prior findings on prednisone for alopecia areata, agreeing that systemic steroids usually do not change the disease course but contesting that most patients have a poor prognosis.
February 2025 in “Journal of Cosmetic Dermatology” This study examined the sensitization potential of common hair care products and found that certain ingredients, like cobalt chloride and nickel sulfate, frequently cause allergic reactions in individuals with hair diseases, providing essential insights for personalized treatment strategies.
December 2023 in “JAAD Case Reports” In this study, a 55-year-old man with a localized patch of alopecia areata achieved hair regrowth through intralesional triamcinolone acetonide injections, demonstrating this treatment as an effective initial therapy for localized alopecia areata.
65 citations
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December 2015 in “Experimental dermatology” This study found that both Th1 and Th2 immune responses, along with IL-23 and IL-32 cytokine pathways, are active in alopecia areata lesions, and corticosteroid injections significantly altered these immune markers.
July 2026 in “Journal of Investigative Dermatology” Alopecia totalis/universalis involves more intense immune activity and inflammation than patchy alopecia areata.
2 citations
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April 2024 in “Advanced Materials” This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.
August 2025 in “Figshare” This meta-analysis found that patients with alopecia areata, especially those with alopecia totalis or alopecia universalis, have an increased risk of cardiovascular disease, possibly due to shared immunological mechanisms and systemic inflammation. Further research is needed to confirm these findings and explore underlying mechanisms.
August 2025 in “Figshare” This meta-analysis found that patients with alopecia areata, especially those with more severe forms like alopecia totalis or universalis, may have an increased risk of cardiovascular disease, suggesting a potential link between the systemic inflammation in AA and cardiovascular risk.
1 citations
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June 2022 in “The Egyptian Journal of Hospital Medicine” This review discusses the epidemiology, clinical characteristics, pathogenesis, and genetic factors of alopecia areata, while stressing the need for targeted and effective treatments, but reports no new clinical results.
June 2023 in “Romanian Medical Journal” In this case study, a 53-year-old female with multiple autoimmune symptoms was diagnosed with Mixed Connective Tissue Disease, confirmed by specific antibodies, and showed significant clinical improvement after one year of treatment.
June 2023 in “JAAD Case Reports” This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.
February 2022 in “CRC Press eBooks” This chapter reviews various hair disorders, focusing on androgenetic and scarring alopecias, and discusses management strategies, but presents no new research findings.
This review discusses fungal skin diseases in goats, highlighting rare vitamin E-, selenium-, and zinc-responsive dermatoses without reporting new clinical results.