research Myeloid Cell-Specific Deletion of mTOR Suppresses Psoriasis-Like Skin Inflammation in C57BL/6 Mice
Targeting mTOR in myeloid cells may help reduce psoriasis symptoms.
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research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Ixekizumab Shows Efficacy and Safety in Patients Who Failed Biweekly Etanercept Therapy: Analysis From UNCOVER-2, a Phase 3 Randomized Clinical Trial in Psoriasis
Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.
research Euphemism as a Core Feature of Patientese: A Comparative Study Between English and French
People use different types of euphemisms for medical terms in English and French, which can cause confusion for non-native speaking healthcare professionals. Also, medical TV shows and the internet might make these terms more technical over time.
research Immune Signatures of Psoriasis: Comparison of Genetic Expression Profiles in Psoriasis Patients After Therapy with Biologic Agents
Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.
research Impact of Ustekinumab on Quality of Life and Sexual Difficulties Associated with Psoriasis: Results from Phase III Clinical Trials
Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.
research Distribution Pattern of Some Glycoconjugates in Hair Follicle Regeneration in Rats
Certain sugars increase in some layers of the hair follicle during the middle of the healing process in rats, which may help improve healing.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
research Lung Cancer Chemoprevention with Retinol Palmitate: Preliminary Data from a Randomized Trial on Stage Ia Non-Small-Cell Lung Cancer
Retinol palmitate may reduce cancer relapses in early-stage lung cancer patients.
research Formulation and Characterization of Transethosomes for Enhanced Transdermal Delivery of Propranolol Hydrochloride
The new gel improves skin delivery of a drug, potentially reducing dose frequency and side effects.
research Determining Safe Excision Limits in FUE: Factors That Affect and a Simple Way to Maintain Aesthetic Donor Density
Researchers concluded that safe hair follicle extraction limits in FUE vary by individual characteristics and proposed a method to calculate these limits to maintain appearance.
research Creating a Natural Hairline in One Session Using a Systematic Approach and Modern Principles of Hairline Design
A single session hair transplant can create a natural hairline using a detailed technique with specific zones and careful planning.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research What's New in the Treatment of Vitiligo
New treatments for vitiligo show promise but still face challenges, especially for hands and feet.
research Notes from the Editor Emeritus
The author believes that in hair restoration, creating an illusion of coverage is more important than perfection, and managing expectations and improving average results should be prioritized over promising unrealistic outcomes.
research High-Performance Liquid Chromatographic Determination of the Enantiomers of the Benzoquinolinone LY 191704, a Human Type 1 5α-Reductase Inhibitor, in Plasma
Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
research Human Exposure to Heavy Metals Over the Last 100 Years
People today have lower levels of arsenic, lead, cadmium, and iron in their hair than people did 100 years ago.
research Ayurvedic Management of Madarosis: A Case Report
Ayurvedic treatment helped a woman regrow her lost eyebrow and eyelash hair.
research Efficacy and Safety of Low-Dose Oral Minoxidil in Men with Androgenic Alopecia
Low-dose oral minoxidil effectively treats male pattern baldness.
research Electrochemical Detector for Liquid Chromatography: Determining Minoxidil in Hair-Growth Pharmaceuticals
The method effectively detects minoxidil in hair-growth products.
research Efficacy of Finasteride Treatment Versus Low-Level Laser in Frontal Male and Female Pattern Hair Loss
Finasteride and low-level laser therapy are similarly effective for frontal pattern hair loss.
research Hair Follicle Regeneration After Implantation of Hair Follicle Cells into Subcutis of Nude Mice
Hair follicle-like structures can form when specific hair cells are mixed and implanted in mice.
research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes
WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.
research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research Guidelines on the Safety of Light-Based Home-Use Hair Removal Devices from the European Society for Laser Dermatology
The ESLD recommends international safety guidelines and standards for home-use light-based hair removal devices.
research Chemical Agents and Peptides Affect Hair Growth
Certain chemicals and peptides can promote hair growth or prevent baldness.
research Editorial
Doctors used to view PCOS too narrowly, but now understand that insulin resistance is a key factor in the condition.
research Hair Removal
Lasers and IPL are the most efficient for short-term hair removal, especially for people with dark hair and light skin, but require multiple sessions for longer-lasting effects.
research Algorithm of Hair Restoration Surgery in Children
Hair restoration in children, tailored to their specific needs, can yield good aesthetic results with minimal complications.
research A Rare Form of Suppurating and Cicatrizing Disease of the Scalp
A rare scalp disease causes hair loss, pus-filled nodules, and scarring.