222 citations
,
September 2016 in “JCI insight” This research overview highlights that although JAK inhibitors show promise as potential treatments for alopecia areata based on recent insights into the disease mechanism, their efficacy has not yet been thoroughly evaluated in a systematic manner.
202 citations
,
June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
89 citations
,
November 2014 in “International Journal of Nanomedicine” This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.
85 citations
,
August 2018 in “Psychological Medicine” This study reported that women with PCOS had higher levels of depression, anxiety, and perceived stress compared to those without PCOS, with stress potentially mediating these associations.
58 citations
,
December 2018 in “Nature Communications” This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.
51 citations
,
May 2010 in “Journal of Drug Targeting” This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.
31 citations
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September 2016 in “PLoS ONE” The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.
26 citations
,
June 2011 in “International Journal of Pharmaceutics” This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.
19 citations
,
September 2020 in “Pharmaceutics” This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.
18 citations
,
January 2020 in “Ecology and evolution” This study analyzed gene expression changes during the autumn coat color change in mountain hares and found conserved gene regulation with snowshoe hares, highlighting its role in seasonal camouflage adaptation.
14 citations
,
January 2025 in “AAPS PharmSciTech” This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.
14 citations
,
February 2021 in “International Journal of Pharmaceutics” In this study, applying deer antler velvet extract-loaded niosomes and microspicules serum to the scalp significantly improved hair growth, melanin content, and skin hydration over 14 to 30 days without causing skin irritation.
13 citations
,
April 2019 in “American Journal of PharmTech Research” In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.
12 citations
,
January 1978 The study observed that Friesian heifers experienced significant adaptation challenges to Kenya's equatorial conditions, taking around 18 months for their coat composition to resemble that of Dutch heifers in summer.
9 citations
,
July 2017 in “Journal of Drug Delivery Science and Technology” This study suggests that a microemulsion formulation of Minoxidil effectively enhances drug delivery through hair follicles, showing significant follicular response alterations in an alopecia model.
7 citations
,
October 2017 in “The Prostate” This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.
6 citations
,
October 2022 in “Journal of cell science” This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
2 citations
,
December 2024 In this study, the researchers observed that the evolution of Curtobacterium flaccumfaciens pv. flaccumfaciens, which causes tan spot in Australian mungbeans, is driven by clonal expansion from existing genetic variations, emphasizing the need for informed breeding strategies to manage resistance against this pathogen.
2 citations
,
September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study reported that AutoML effectively modeled itching and pain development, as well as app use, in patients with chronic eczema or psoriasis using a smartphone monitoring app, revealing that factors like BMI, age, and disease activity significantly influenced app engagement.
2 citations
,
August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
1 citations
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July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study re-analyzed single cell RNAseq data and confirmed longstanding views on keratin gene regulation in keratinocytes, while challenging assumptions about their role in cellular differentiation states.
January 2026 in “ITM Web of Conferences” This review examines the current state of automated vitiligo detection systems, noting a lack of large, diverse datasets and consistent imaging conditions, while comparing traditional and modern machine learning approaches to improve reliability and applicability.
December 2024 in “arXiv (Cornell University)” In this study, researchers devised a stochastic hair growth model influenced by regular haircuts, using a process that undergoes linear growth subject to random resets, and used it to theoretically determine an ideal haircut routine.
November 2023 in “Dermatology Research and Reports” This study reported that a 1% ivermectin topical cream for rosacea was stable over six months, showing no significant changes in key physical properties or microbial contamination, suggesting it may reduce chronic antibiotic use in rosacea treatment.
This study identified new geometric and mechanical parameters for curly and kinky/coily hair, which may inform more effective personal care products tailored to these hair types.
January 2023 in “International Journal of Research Publication and Reviews” This review details the causes, symptoms, and treatments for dandruff, emphasizing herbal ingredients with anti-dandruff properties used in shampoos and exploring their antifungal and anti-inflammatory mechanisms. It highlights dandruff's exploitation by personal care companies due to the lack of medical interventions.
This study used quantitative methods to identify new geometric and mechanical parameters of curly and kinky/coily hair, aiming to improve classification and develop better personal care products for these hair types.
June 2015 in “Biomedical and biopharmaceutical research” This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.
January 2006 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” This study found that carbon and nitrogen isotope analysis of cattle hair reflects dietary and farm system differences, offering insights into cattle nutritional ecology and agroecosystem characteristics.