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This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.

This review discusses the biology of hair follicle stem cells and highlights their potential for applications in regenerative medicine, drug, and gene delivery, but reports no new clinical results.

This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.

This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.

This review discusses the development and application of multiphoton microscopy in dermatology, highlighting its advantages and potential future research directions without reporting new clinical results.

This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.

This review discusses the use of ablative and nonablative fractional resurfacing for enhanced topical drug delivery in dermatology and reports no new clinical results; further studies are needed to explore these methods.

This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.

This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.

This review discusses recent advances in monophosphate prodrug strategies for HCV drug discovery, aiming to enhance oral absorption and stability, and reports no new clinical results.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

This study found that loading CoQ10 into a protransfersomal emulgel improved its stability and anti-ageing effects in UV radiation skin-aged induced-mice, without causing skin irritation.

This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.

This study identified several compounds from traditional Chinese medicines that may inhibit prostaglandin D2 synthase, potentially providing promising candidates for treating androgenic alopecia with minimal adverse skin reactions.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.

This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.

This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

This review examines the role of cyclodextrins in improving the solubility, stability, and bioavailability of steroid drugs but does not report new experimental findings.

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.

This review discusses nanostructured lipid carriers and their potential applications in pharmaceuticals and food, offering no new clinical findings but highlighting recent advancements and patents.