48 citations
,
April 2019 in “ACS Applied Materials & Interfaces” In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
31 citations
,
January 2012 in “Skin Research and Technology” In this study, curcumin was successfully encapsulated in ethyl cellulose and its blend with methyl cellulose, enhancing its skin penetration efficacy through o/w and w/o lotions compared to water suspensions.
1 citations
,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
November 2024 in “International Journal of Research and Review” This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
122 citations
,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” This review discusses the mechanisms and storage of particles in hair follicles and presents no new experimental results, highlighting the need for further research in their safe application in dermatology and cosmetics.
November 2025 in “Scholarly Commons (Embry–Riddle Aeronautical University)” This review discusses how urban air pollutants may influence the regulation of JAK3 signaling in alopecia areata and reports no new experimental results; the authors integrate existing data to map potential pathways and biomarkers.
43 citations
,
August 2016 in “International Journal of Nanomedicine” This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.
5 citations
,
January 2008 in “Recent Patents on Drug Delivery & Formulation” This review compiles patents for nanoparticulate drug delivery systems, discussing preparation methods, therapeutic applications, and commercialization, but reports no new experimental results.
11 citations
,
July 2020 in “Scientific Reports” This study suggests that statins may be linked to various ovary and uterus related adverse events, highlighting the need for monitoring in clinical practice.
January 2002 in “HAL (Le Centre pour la Communication Scientifique Directe)” In this study, researchers characterized a dehydroepiandrosterone hydroxylating enzyme system in hair follicles similar to the liver monooxygenase system, noting its inhibition by carbon monoxide and its dependence on NADPH.
11 citations
,
June 1979 in “British Journal of Dermatology” This study found that the dehydroepiandrosterone hydroxylating enzyme system in hair follicles is similar to the liver monooxygenase system, sharing characteristics such as inhibition by carbon monoxide and dependency on NADPH.
89 citations
,
October 1996 in “Dermatologic Clinics” This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
4 citations
,
December 1999 in “PubMed” This review discusses the potential of drug therapies like finasteride for treating androgenetic alopecia, highlighting its ability to prevent hair loss and promote regrowth in clinical trials with men.
28 citations
,
January 2017 in “EBioMedicine” This study discusses potential anti-inflammatory roles of endocannabinoid system modulation and phytocannabinoids in skin health, but reports no new clinical results; the authors emphasize the need for further clinical exploration.
This study developed nanoparticulate systems for caffeine delivery in hair follicles, demonstrating effective caffeine loading and release, as well as successful imaging within model hair follicles.
57 citations
,
June 1999 in “Dermatologic surgery” This review discusses various hair removal methods, focusing on laser-assisted systems, and reports no new clinical results.
14 citations
,
March 2019 in “European journal of pharmaceutics and biopharmaceutics” This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.
122 citations
,
March 2013 in “Expert opinion on drug delivery” This review summarizes drug delivery strategies to hair follicles, highlighting physicochemical factors affecting penetration and the use of stimuli-responsive particulate carriers, but reports no new clinical findings.
17 citations
,
April 2021 in “Biointerface Research in Applied Chemistry” This review discusses nanostructured lipid carriers and their potential applications in pharmaceuticals and food, offering no new clinical findings but highlighting recent advancements and patents.
June 2018 in “International journal of trend in scientific research and development” This review discusses the formulations, mechanisms, and physiological aspects of hair cosmetics and types, but reports no new results, suggesting a foundation for future hair research.
This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.
January 2022 in “Revista Dermatológica Centro Uraga” In this article, the authors report a case of nearly simultaneous herpes zoster and COVID-19 in a non-immunosuppressed patient.
March 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that faster algorithms for inferring ancestry in genomic data can better capture historical and functional insights into genome variation than traditional methods in large datasets like the UK Biobank.
December 2019 in “RIUnB Institutional Repository (University of Brasília)” This study developed two types of polymeric nanoparticles containing clindamycin phosphate for potential topical acne treatment and found that the NP-AH-CDM-4 formulation preferentially penetrated hair follicles even with sebaceous obstruction, suggesting its promise for more effective acne therapy without causing skin irritation.
23 citations
,
July 2015 in “PubMed” This review summarizes existing literature on PDGF's role in adipose-derived stem cells, highlighting PDGFRβ's functions in inhibiting white adipocyte differentiation and promoting proliferation and angiogenesis.
10 citations
,
April 2007 in “Aesthetic Plastic Surgery” This study demonstrated the feasibility of a new patient-controlled method for tissue expansion that achieved full expansion in about 3 weeks with minimal complications after mastectomy.
This review highlights the multifaceted roles of skin in immune and endocrine functions, stressing its contributions to psycho-immunological and psycho-endocrine responses, but presents no new research findings.
215 citations
,
March 2018 in “Archives of Toxicology” This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.
349 citations
,
January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.