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      research Diseases of the Canine Prostate Gland

      1 citations , August 2022 in “Veterinary medicine and science”
      This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.
      A Review on Cryptorchidism-Induced Alopecia in Dogs

      research A Review on Cryptorchidism-Induced Alopecia in Dogs

      May 2025 in “International Journal of Innovations in Science Engineering and Management.”
      This study reviewed the literature on cryptorchidism in dogs and found it may be associated with dermatological issues like alopecia, with surgical intervention and cyclosporine offering partial benefit.
      Estimating the Contribution of the Prostate to Blood Dihydrotestosterone

      research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone

      28 citations , November 2003 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.
      Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer

      research Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer

      23 citations , January 2014 in “International Journal of Biological Sciences”
      This study found that African American men with prostate cancer have higher rates of somatic and germline androgen receptor mutations than Caucasian American men, which may contribute to ethnic differences in disease progression and outcomes.
      Update on Idiopathic Hirsutism: Diagnosis and Treatment

      research UPDATE ON IDIOPATHIC HIRSUTISM: DIAGNOSIS AND TREATMENT

      6 citations , July 2013 in “Acta Clinica Belgica”
      This review discusses idiopathic hirsutism and suggests that combination treatment, including androgen suppression and cosmetic methods, is most effective, but notes that its pathogenesis remains unclear.
      Role of 5α-Reductase in Health and Disease

      research 9 Role of 5α-reductase in health and disease

      101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”
      This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.
      Idiopathic Hirsutism: Androgen Role and Treatment Options

      research Idiopathic Hirsutism*

      47 citations , August 2000 in “Endocrine Reviews”
      This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.
      New Dimensions in Hirsutism

      research New dimensions in Hirsutism

      19 citations , July 2006 in “Lasers in medical science”
      This review discusses hormone-related hair growth, hirsutism treatment options, and the combination of eflornithine and laser hair removal, reporting no new clinical results.
      Comprehensive Clinical Management of Hirsutism

      research Comprehensive clinical management of hirsutism

      14 citations , March 2010 in “Gynecological endocrinology”
      This article provides an overview of treatment options for hirsutism, summarizing both pharmacologic and non-pharmacologic approaches, but reports no new clinical results.
      Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition

      research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition

      451 citations , March 2005 in “Endocrine Reviews”
      This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
      Selective Non-Steroidal Inhibitors of 5α-Reductase Type 1

      research Selective non-steroidal inhibitors of 5α-reductase type 1

      49 citations , January 2004 in “Journal of steroid biochemistry and molecular biology/˜The œJournal of steroid biochemistry and molecular biology”
      This review discusses the development and selectivity of 5 alpha-reductase inhibitors, particularly non-steroidal ones, and reports no new clinical trial results.
      Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin

      research Azasteroids as inhibitors of testosterone 5α-reductase in mammalian skin

      34 citations , February 1993 in “Journal of steroid biochemistry and molecular biology/˜The œJournal of steroid biochemistry and molecular biology”
      This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.
      Androgen Antagonists in Androgen Target Tissues

      research Androgen antagonists in androgen target tissues

      27 citations , January 1984 in “Pharmacology & Therapeutics”
      This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.
      Finasteride: The First 5α-Reductase Inhibitor

      research Finasteride: The First 5α-Reductase Inhibitor

      23 citations , July 1993 in “Pharmacotherapy”
      Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
      Cyproterone Acetate: A Genotoxic Carcinogen?

      research Cyproterone Acetate: A Genotoxic Carcinogen?

      1 citations , May 2001 in “Pharmacology & Toxicology”
      This review discusses the preclinical findings on cyproterone acetate and suggests that while it has a low potential cancer risk for patients, its tumor effects in female rats may involve both genotoxic and mitogenic mechanisms.
      Male Androgenetic Alopecia

      research Male androgenetic alopecia

      100 citations , April 2010 in “Expert Opinion on Pharmacotherapy”
      This article reviews existing treatments for male-pattern hair loss, noting that while they can slow progression, they generally achieve only partial hair regrowth.

      research Anabolic effects of testosterone are preserved during inhibition of 5α-reductase

      42 citations , May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism”
      In this animal study, administering testosterone alongside a 5α-reductase inhibitor counteracted testosterone's effects on prostate enlargement while preserving its beneficial effects on muscle and bone.
      Penis Endocrinology

      research Penis Endocrinology

      November 2017
      This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.
      Hirsutism

      research Hirsutism

      May 2006 in “Women's Health Medicine”
      This review examines the causes, assessment, and treatments of hirsutism and highlights the need for future research in managing this condition but presents no new research findings.
      Hormesis And Medicine: Biphasic Dose-Response Relationship

      research Hormesis and medicine

      127 citations , June 2008 in “British Journal of Clinical Pharmacology”
      This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.