research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
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research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Peroxisome Proliferator-Activated Receptors (PPARs) and PPAR Agonists: The Future in Dermatology Therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Polycystic Ovary Syndrome: Etiology, Pathogenesis, and Diagnosis
The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
research The Clinical Presentation of Systemic Lupus Erythematosus
Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.
research Beyond DNA-Targeting in Cancer Chemotherapy: Emerging Frontiers - A Review
New cancer treatments aim to reduce side effects and improve effectiveness.
research Molecular Docking Simulation Studies on Potent Butyrylcholinesterase Inhibitors Obtained from Microbial Transformation of Dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research Mitoxantrone
Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component
Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
research Therapeutic Updates on Lichen Planopilaris and Frontal Fibrosing Alopecia: A Systematic Review
Antimalarial agents are effective for LPP, and intralesional steroids are effective for FFA.
research Post-Partum Pituitary Insufficiency and Livedo Reticularis Presenting a Diagnostic Challenge in a Resource-Limited Setting in Tanzania: A Case Report, Clinical Discussion, and Brief Review of Existing Literature
Early diagnosis and hormone therapy can significantly improve outcomes for post-partum pituitary insufficiency in resource-limited settings.
research Pathophysiology of Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata
Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Restoration of Hair Growth with Topical Diphenylcyclopropenone in Mouse and Rat Models of Alopecia Areata
Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
research The Pathophysiology of Polycystic Ovary Syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Facial Feminization Surgery and Facial Gender Confirmation Surgery
The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.
research Cyclosporine A Stimulated Hair Growth from Mouse Vibrissae Follicles in an Organ Culture Model
Cyclosporine A was found to increase hair growth in mouse whisker follicles.
research Tourniquet Syndrome: Importance of Systematic Analysis of Families' Social Conditions to Detect Neglect Situations
Checking family social conditions in tourniquet syndrome cases can help find neglect.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation
Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
research Surgical Strategies for Scalp and Forehead Injuries and Hair Loss
The document concludes that successful surgical repair of scalp and forehead issues requires careful planning and various techniques depending on the injury or defect size.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Drug Treatment of Acute Leukemia: Current Status
Treatments for acute leukaemia lead to high remission rates, but relapses occur, requiring ongoing advancements in care.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Madarosis
Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.
research Herbal Treatment for Dermatologic Disorders
Some herbal treatments are effective for skin disorders, but more research and regulation are needed.
research SlPHL1, a MYB-CC Transcription Factor Identified from Tomato, Positively Regulates the Phosphate Starvation Response
SIPHL1 from tomato enhances plants' response to low phosphate levels.