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Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

The document is a detailed medical reference on skin and genetic disorders.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

The document concludes that proper recognition and treatment of skin appendage disorders are important for management.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Four-amino acid part makes enzyme sensitive to finasteride.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Finasteride harms invertebrates' survival and burial ability.