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The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Hair loss in women may have causes other than hormones.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The normal human prostate does not significantly affect blood DHT levels.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.