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Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

New alopecia treatments aim for better results and fewer side effects.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Some alternative treatments for hair loss might work, but more research is needed.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Adrenal disorders can cause lasting brain and behavior issues in children.

People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Fullerene nanomaterials help hair grow faster and increase hair follicles.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.