research A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Researchers developed a new, precise method to measure hair loss in mice using image analysis.
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research Expanding Research and Development of Novel Agents for the Treatment and Prevention of Chemotherapy-Induced Alopecia
No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.
research Skin Diseases in Pregnancy
Pregnancy can cause various skin changes and diseases, requiring careful treatment to protect the baby.
research How Far Should We Investigate Diffuse Alopecia in Women?
Routine thyroid tests for diffuse alopecia in women may not be necessary, but checking for iron deficiency anemia could be useful.
research Contributions of Experimental Animal Research to Dermatology
Animal research has greatly advanced dermatology.
research Vitamin D: A Bridging Element for Wellness; A Case Study on Vitamin D Deficiency and Its Association with Alopecia Areata and Other Conditions
Vitamin D is crucial for health, and deficiency can cause hair loss and other health issues.
research Unlocking the Genetic Secrets of Dorper Sheep: Insights Into Wool Shedding and Hair Follicle Development
This study explores the genetic mechanisms behind wool shedding and hair follicle development in Dorper sheep, known for their natural wool shedding. Researchers conducted transcriptome analysis on skin tissues from adult Dorper ewes, identifying thousands of differentially expressed transcripts and key signaling pathways such as Rap1, estrogen, PI3K-Akt, and MAPK involved in hair follicle development. Core genes like DBI, FZD3, KRT17, ZDHHC21, TMEM79, and HOXC13 were found to be influential. The study also highlights the role of alternative splicing, particularly the isoforms of ZDHHC21, in hair follicle development. These findings provide insights into the genetic basis of hair follicle development in sheep and have potential implications for understanding human hair growth.
research Alpha Smooth Muscle Actin Role in Androgenetic Alopecia Pathogenesis
Reduced alpha smooth muscle actin may cause hair loss in androgenetic alopecia.
research Impact of Vitamin D Supplementation in PCOS and Non-PCOS Patients
PCOS patients, especially obese ones, often lack vitamin D and may need supplements and lifestyle changes.
research Multiple Endocrine Defects in Adult-Onset Sprouty1/2/4 Triple Knockout Mice
Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
research Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects
Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
research Vitamin D-Dependent Rickets Type II
A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.
research Frontal Fibrosing Alopecia: Clinical and Histopathological Characteristics of Mexican Patients - An Original Research Study and Review of Literature
Frontal Fibrosing Alopecia mainly affects postmenopausal Mexican women, requiring early detection to prevent permanent hair loss.
research The Role of Vitamin D3 Deficiency in the Etiopathogenesis of Autoimmune Thyroid Diseases
Low vitamin D3 is not linked to different levels of thyroid hormones in people with autoimmune thyroid disease.
research Vitamin D in Dermatology and Cosmetology
Vitamin D is crucial for skin health and managing skin diseases.
research Prostate Specific Antigen as a Predictive Factor for Androgenemia in Women
PSA can help diagnose high androgen levels in women.
research Status of Serum Vitamin D Level Among Patients With Alopecia Areata in a Tertiary Care Hospital, Bangladesh
People with alopecia areata have much lower Vitamin-D levels than healthy individuals.
research Common Dermatologic Disorders in Down Syndrome: Systematic Review
People with Down syndrome have a higher risk of skin disorders and need better screening and treatment.
research Drug Armamentarium for Alopecia Areata
No cure exists for alopecia areata, and treatments are personalized.
research A Direct Link Between Prss53, Hair Curvature, and Skeletal Dysplasia
The gene Prss53 affects hair shape and bone development in rabbits.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research Very Late Onset Trichotillomania: A Case Report
A man developed a rare late-onset hair-pulling disorder, usually seen in younger people.
research Worldwide Cancer Incidences Analyzed by Sex, Age, and Skin Type Over Time (1955-2007), Excluding Skin Cancer, Reveals Important Carcinogenic Drivers
Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
research Autoimmune Polyendocrine Syndrome Type 1: A Case Report from Bangladesh
A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.
research The Skin Findings of Pregnant Women and Our Treatment Choices: A Turkish Experience Over a 5-Year Survey
Turkish pregnant women commonly experienced skin issues like itching and acne, and doctors mainly used topical treatments due to safety concerns during pregnancy.
research The Acne Hormones
Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.
research Poikiloderma, Hyperpigmentation, Alopecia, Hypohidrosis, Malformed Bones, Lymphedema of the Legs and Decreased Cortisol Level: A New Entity?
A new medical syndrome may include skin changes, hair loss, sweating issues, bone malformations, leg swelling, and low cortisol.
research Obstetric Dermatology
The document concludes that managing skin conditions during pregnancy is important and requires specialized care.