research Evaluation of Paraoxonase 1 Serum Level in Male Androgenetic Alopecia Patients
This study found that male patients with androgenetic alopecia had lower serum levels of the antioxidant enzyme paraoxonase 1 compared to healthy controls.
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30 / 81 results research The role of Paraoxonase 1 in Alopecia Areata, a Marker and a Severity Index
This study found that patients with alopecia areata have significantly lower serum PON1 levels compared to controls, indicating a potential link between oxidative stress and the pathogenesis of the disease.
research 475 Paraoxonase 1 (PON1) L55M and Q192R polymorphisms, lipid profiles and psoriasis
This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.
research Serum Paroxonase 1 Level and Androgenetic Alopecia: Correspondence
This study suggests that serum paroxonase 1 levels are decreased in patients with androgenetic alopecia and may serve as a useful biomarker for this condition.
research Serum paroxonase 1 level may be an indicator and predictor of the severity of androgenetic alopecia
This study found that androgenetic alopecia patients had significantly lower serum levels of paraoxonase 1, which correlated with disease severity and suggests a role of oxidative stress in its pathogenesis.
research Paraoxonase Enzyme Activity and Determination of Phenotypic Polymorphism in Patients with Acne Vulgaris
This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.
research Investigation of Paraoxanase Enzyme Polymorphism in Patients with Alopecia Areata
This study found no statistically significant relationship between androgenic alopecia and the PON1 ML55 and QR192 genetic polymorphisms, despite a higher frequency of the PON 55 L allele in patients.
research The impact of oxidative stress in the androgenic alopecia in women
Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.
research Oxidative stress and antioxidant markers in patients with alopecia areata: A comparative cross-sectional study
This study found that patients with alopecia areata had higher levels of oxidative stress markers and lower antioxidant enzyme activity compared to healthy controls.
research The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis.
This study found that alopecia areata patients have elevated oxidative stress markers, such as OSI and MDA, and reduced antioxidant enzyme activities, suggesting a significant role for oxidative stress in the disease and potential value in targeting it therapeutically.
research Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata
This study found that in people with alopecia areata, oxidative stress indicators were higher and specific enzyme activities were lower compared to healthy controls, suggesting oxidative stress's significant role in disease pathogenesis.
research 474 Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility
This study identified that dominant mutations in the KLHL24 gene cause epidermolysis bullosa through dysregulated autoubiquitination, leading to excessive degradation of keratin 14.
research Skin features in myotonic dystrophy type 1: An observational study
This study found that adult patients with Myotonic Dystrophy type 1 exhibited a higher prevalence of various morphofunctional, inflammatory, and proliferative skin disorders compared to healthy controls.
research Las alteraciones metabólicas y funcionales asociadas a la COVID-19
This article provides tables summarizing various medical conditions and symptoms related to COVID-19, sepsis, and cardiovascular issues, but it does not report new research findings.
research New drugs under investigation for the treatment of alopecias
This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.
research Protective Activity against Oxidative Stress in Dermal Papillae with Extracted Herbal Essential Oils
This study found that essential oils boost hair growth activity in dermal papilla cells by scavenging reactive oxygen species and upregulating growth factor biomarkers.
research Metabolic risk in PCOS: phenotype and adiposity impact
This review discusses how women with PCOS have an increased risk of insulin resistance and cardiometabolic features regardless of body fat, and calls for targeted prevention and management strategies.
research Role of Oxidative Stress in Polycystic Ovary Syndrome
This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.
research Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review
This review suggests that quercetin supplementation may benefit ovarian functions and hormonal levels in polycystic ovary syndrome, though further high-quality trials are needed for confirmation.
research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses
This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
In this study, researchers used an evolutionary-rate-based method to identify genetic elements associated with reduced hair in mammals, finding a dichotomy between accelerated coding sequences and noncoding regulatory elements influencing hair growth.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research Eco-Friendly Extraction and Formulation of Black Sea Shark Liver Oil-Based Emulgel for Anti-Inflammatory and Healing Dermatocosmetic Applications
This study explored Black Sea shark liver oil-based emulgels, finding that the addition of borage oil (Gel 2) enhanced the anti-inflammatory and wound healing properties compared to shark liver oil alone (Gel 1) and a reference diclofenac gel, suggesting promising eco-friendly applications in dermatocosmetics.
research Polycystic Ovary Syndrome Is a Challenging Problem in Women
This research suggests that phytoestrogen-rich herbal extracts may help reduce hyperandrogenism, insulin resistance, and ovarian weight while promoting ovulation in polycystic ovarian syndrome, indicating potential for discovering new bioactive compounds.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Formulation and Evaluation of Herbal Shampoo
In this study, researchers evaluated a multi-herbal shampoo made with natural components like aloe and hibiscus, reporting it as safer and more effective than synthetic options, though consumer acceptance remains a challenge.
research The Role of Vitamins and Minerals in Hair Loss: A Review
This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Systemic Comorbidities in Korean Patients with Rosacea: Results from a Multi-Institutional Case-Control Study
In this study, Koreans with rosacea showed higher odds of experiencing various systemic comorbidities, including autoimmune diseases and certain cancers, compared to controls.