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Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.

Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Targeting TGFβ can improve skin immunity in older people.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Different types of cells in the eye express specific keratins at various stages of development.

VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.

Treg cells help repair and regenerate tissues by interacting with local cells.

ADSCs help in wound healing and skin regeneration but need more research for full understanding.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.

New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Hair follicle regeneration possible, more research needed.

All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Different types of skin cells play specific roles in development, healing, and cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.