28 citations
,
January 2021 in “Skin appendage disorders” This study observed that telogen effluvium, or acute hair loss, often occurs 1 to 3 months after SARS-CoV-2 infection, earlier than classic telogen effluvium.
28 citations
,
February 2016 in “International Journal of Nanomedicine” This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.
27 citations
,
November 2020 in “International Journal of Dermatology” This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.
26 citations
,
February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
26 citations
,
January 1992 in “Cancer investigation” This study found that N-acetylcysteine effectively prevented cyclophosphamide-induced alopecia in rats, and ImuVert plus N-acetylcysteine prevented alopecia from a cyclophosphamide-cytarabine combination.
25 citations
,
July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery” This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.
24 citations
,
August 2018 in “Journal of Ayurvedic and herbal medicine” In this review, the authors summarize the phytochemistry, pharmacology, and medicinal uses of Hibiscus rosa sinensis, highlighting its various benefits such as hypotensive and anti-inflammatory effects, while noting the need for more research on its specific mechanisms and potential toxicities.
23 citations
,
October 2018 in “Expert Opinion on Drug Safety” This review discusses the safety concerns associated with new treatments for non-scarring alopecias, highlighting that while these therapies such as JAK inhibitors and oral minoxidil show efficacy in hair regrowth, their safety profiles vary significantly, requiring careful consideration of benefits and risks.
23 citations
,
June 2018 in “Facial Plastic Surgery” This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.
22 citations
,
April 1998 in “Dermatologic Clinics” This article reviews the therapeutic use of interferons and other cytokines in various viral, tumorous, and inflammatory diseases, discussing their biological effects and potential future applications without presenting new experimental results.
20 citations
,
October 2018 in “American Journal of Clinical Dermatology” This article reviews drug-induced pigmentation and reports no new clinical findings, highlighting difficulty in confirming drug associations due to factors like delayed onset and polypharmacy.
19 citations
,
October 2020 in “Biomedical Microdevices” This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.
19 citations
,
March 2018 in “Expert Opinion on Drug Safety” In this narrative review, the researchers reported that the overall safety profile of drugs used for treating spondyloarthritis is generally good, with serious adverse events being rare, but emphasized the need for rheumatologists to tailor treatments and closely monitor patients for potential adverse events.
18 citations
,
March 2006 in “Expert Review of Neurotherapeutics” This review outlines strategies for preventing, identifying, and managing complications related to current MS therapies and reports no new clinical results, emphasizing the growing complexity in MS treatment regimens.
18 citations
,
November 1994 in “Histochemical Journal” This study explored the localization of phenolsulphotransferase in human embryonic and fetal kidneys, finding distinct patterns of PST immunoreactivity in developing mesonephric and metanephric structures over time.
17 citations
,
April 2021 in “Clinical Phytoscience” This review discusses the ethnobotanical uses and phytochemistry of Plumbago zeylanica L., highlighting its potential pharmacological benefits for conditions such as diabetes and cardiovascular disorders, but reports no new experimental findings.
17 citations
,
March 2006 in “BJU international” Using buccal mucosa for hypospadias repair in children is effective and reduces complications.
16 citations
,
May 2019 in “International Journal of Women's Dermatology” This study reviewed and categorized dermatological drugs for pregnancy and lactation according to new FDA labeling guidelines, which replaced simplistic letter categories with detailed information, aiming to improve prescribing decisions by addressing both maternal and paternal reproductive potential.
15 citations
,
May 2020 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.
15 citations
,
November 2017 in “Drug Development and Industrial Pharmacy” This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
15 citations
,
September 2013 in “Pharmaceutical Biology” This study found that Zizyphus jujuba fruit aqueous extract may reduce nephrotoxicity caused by ibuprofen in rats by lowering serum urea and creatinine and improving kidney antioxidant enzyme activities.
15 citations
,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This study observed that direct hair transplantation, as a modification of follicular unit extraction, was effective in improving baldness in the majority of treated male patients.
14 citations
,
May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.
13 citations
,
March 2019 in “Pharmacology Research & Perspectives” This study analyzed CADR reports in Singapore, finding nonsteroidal anti-inflammatory drugs, antibiotics, and iohexol frequently associated with serious skin reactions like rash and angioedema, with trends varying by demographics.
12 citations
,
November 2022 in “Archives of Dermatological Research” This review summarizes existing and new cases of generalized pustular psoriasis and acute generalized exanthematous pustulosis associated with COVID-19, noting that over half lacked a known drug trigger.
12 citations
,
January 2016 in “Endocrinology, diabetes & metabolism case reports” This report describes a 19-year-old male with 49,XXXXY syndrome receiving testosterone replacement therapy, which led to improvements in reproductive development, metabolism, and social interaction after a year of treatment.
11 citations
,
June 2011 in “Expert Review of Dermatology” This review covers various skin-related adverse drug reactions and lists common drugs associated with these reactions but presents no new clinical findings.
11 citations
,
April 1990 in “Australasian Journal of Dermatology” This study found that 2% minoxidil solution significantly increased non-vellus hair counts and regrowth rates compared to placebo in men with early androgenic alopecia, suggesting it is an effective treatment.
10 citations
,
January 2023 in “Molecular and Cellular Biochemistry” This review discusses the potential therapeutic role of the edible plant Solanum nigrum for managing COVID-19 symptoms and post-COVID complications based on in silico docking and pharmacological studies, but reports no new clinical results.
8 citations
,
June 2021 in “Journal of Cosmetic Dermatology” This review details various skin manifestations linked to COVID-19 and highlights dermatitides caused by personal protective equipment, emphasizing the need for accurate diagnosis and prompt treatment.