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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Lower hair copper and copper-to-zinc ratio are linked to more severe coronary artery disease.

Women with PCOS have more insulin resistance and are more likely to have heart-related health issues, with insulin resistance being a bigger factor than β-cell problems.

N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.

Vasodilators may worsen abdominal aortic aneurysm.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.

Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.

Combining lifestyle changes and medication is most effective for managing PCOS symptoms.