150 citations,
March 1995 in “Annals of Oncology” Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.
22 citations,
July 2014 in “Hormones” Metformin may help treat neuroendocrine tumors.
October 2021 in “International journal of basic and clinical pharmacology” Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.
21 citations,
November 2021 in “Cells” Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
505 citations,
December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
72 citations,
October 1992 in “Archives of Dermatology” Recognizing certain rashes can lead to earlier cystic fibrosis diagnosis and better outcomes.
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January 2013 in “Molecular genetics and metabolism” Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.
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December 2010 in “Journal of thoracic oncology” New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
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October 2023 in “Journal of the Endocrine Society” Finasteride may worsen blood sugar control in diabetic patients.
11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
2 citations,
December 2022 in “Journal of Biochemistry and Molecular Biology” Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
3 citations,
December 2021 in “Frontiers in endocrinology” A new mutation in the DCAF17 gene was found in a Chinese family, causing Woodhouse-Sakati syndrome and diabetes.
February 1960 in “Journal of the American Medical Association” Treatments for hair loss include estrogen therapy and special shampoos.
November 2022 in “Journal of the Endocrine Society” Excessive iodine from a cystic fibrosis supplement can cause hypothyroidism.
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June 2005 in “Clinical Oncology” Orlistat might block the body's ability to absorb thyroid medication.
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June 2005 in “Clinical Oncology” A man's bald spot grew hair after starting cancer treatment with gefitinib.
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July 2012 in “Regenerative Medicine” New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.
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February 2012 in “Clinical Neurology and Neurosurgery” Dystonia may be part of PAS-4 and linked to immune issues.
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May 2018 in “International Journal of Current Microbiology and Applied Sciences” Certain plant compounds can help treat diabetes.
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January 2011 in “International journal of trichology” A 3-year-old boy had a rare hairball condition usually seen in teenage girls.
February 2012 in “Clinical and Experimental Dermatology” Many adult women experience unexplained excessive hair shedding, often starting before age 40.
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October 2018 in “Medical Science Monitor” Women with PCOS have lower amylin levels, which are not related to their body weight.
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November 1993 in “Mammalian Genome” A gene mutation in mice causes permanent hair loss and skin issues.
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July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
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July 2004 in “Apmis” Fluorescent proteins help visualize and understand tumor blood vessel growth.
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January 2012 in “Indian Journal of Endocrinology and Metabolism” Old drugs are often used for new, different medical purposes in endocrine pharmacology.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
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May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.