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    Did you mean Pancreatic Carcinoma?
    Glossary Pancreatic Carcinoma

    malignant tumor originating in the pancreas, often aggressive

    Pancreatic carcinoma, commonly known as pancreatic cancer, is a malignant tumor that originates in the tissues of the pancreas, an organ located behind the stomach that plays a crucial role in digestion and blood sugar regulation. The most common type is pancreatic adenocarcinoma, which arises from the exocrine cells responsible for producing digestive enzymes. This type of cancer is particularly aggressive and often diagnosed at an advanced stage due to its subtle early symptoms.

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    1. Case 5 Small Animal Dermatology · 2019
    2. Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese 2022
    3. RSPO1, a potent inducer of pancreatic β cell neogenesis Cell Reports Medicine · 2025 · 1 citations
    4. The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1 Journal of Biological Chemistry · 2000 · 119 citations
    5. The human keratins: biology and pathology Histochemistry and Cell Biology · 2008 · 1398 citations
    6. The keratin 19 promoter is potent for cell-specific targeting of genes in transgenic mice Gastroenterology · 2001 · 66 citations
    7. The Double-Edged Proteins in Cancer Proteomes and the Generation of Induced Tumor-Suppressing Cells (iTSCs) Proteomes · 2023 · 4 citations
    8. The relationship between keratin 18 and epithelial-derived tumors: as a diagnostic marker, prognostic marker, and its role in tumorigenesis Frontiers in Oncology · 2024
    9. Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate Genes · 2019 · 28 citations
    10. Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice The FASEB Journal · 2004 · 49 citations
    11. Lineage potential, plasticity and environmental reprogramming of epithelial stem/progenitor cells Biochemical Society Transactions · 2014 · 4 citations
    12. The roles of Wnt/β‐catenin pathway in tissue development and regenerative medicine Journal of Cellular Physiology · 2017 · 89 citations
    13. K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors Scientific Reports · 2021 · 4 citations
    14. Transforming growth factor-β in stem cells and tissue homeostasis Bone Research · 2018 · 245 citations
    15. Somatic Mutations in Normal Tissues: New Perspectives on Early Carcinogenesis Annual Review of Cancer Biology · 2023 · 13 citations
    16. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer Nature Reviews Genetics · 2018 · 124 citations
    17. In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models Frontiers in Bioengineering and Biotechnology · 2023
    18. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    19. Organoid technology for tissue engineering Journal of Molecular Cell Biology · 2020 · 70 citations
    20. Role of regeneration in tissue repairing and therapies Journal of regenerative medicine & tissue engineering · 2015 · 6 citations
    21. Pharmacological Activity of Cepharanthine 2023 · 3 citations
    22. SOX9 in organogenesis: shared and unique transcriptional functions Cellular and Molecular Life Sciences · 2022 · 10 citations
    23. Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker Stem Cell Research & Therapy · 2025 · 9 citations
    24. Ontogeny of Skin Stem Cells and Molecular Underpinnings Current Issues in Molecular Biology · 2024 · 7 citations
    25. Current Biomedical Applications of 3D-Printed Hydrogels Gels · 2023 · 24 citations
    26. Liposome-Based Carriers for CRISPR Genome Editing International Journal of Molecular Sciences · 2023
    27. Keratin intermediate filaments in the colon: guardians of epithelial homeostasis International journal of biochemistry & cell biology · 2020 · 38 citations
    28. Tracking adult stem cells EMBO Reports · 2011 · 180 citations
    29. Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective Trends in Cell Biology · 2023 · 45 citations
    30. British Society for Dermatopathology British Journal of Dermatology · 2011