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Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Hair changes can indicate systemic diseases or medication effects.

Certain nutrients can help keep skin healthy as we age.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.

Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.

New genetic mutations linked to rare skin disorders were found in three newborns.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.

A mutation in the FAM83G gene is linked to skin and hair abnormalities in two related individuals.

Brodalumab effectively treated a man's severe hand and foot psoriasis.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

Acitretin helped improve hand mobility and skin condition in a patient.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Tofacitinib improved hair loss and skin symptoms in a patient after secukinumab caused hair loss.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

A girl with a rare skin condition improved after one month of treatment with acitretin.

Topical 6% salicylic acid effectively reduced skin plaques in a patient with wooly hair and palmoplantar keratoderma.

A patient got a skin reaction on their hands and feet after using secukinumab for psoriasis.

Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.

People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

Carbamazepine caused hair loss and skin eruptions in a woman, which improved after stopping the medication.

The woman was diagnosed with lichen sclerosus, a rare skin condition, after initial misdiagnosis and ineffective treatments.